【摘要】 猪瘟病毒(CSFV)是一种常见的猪场感染病毒，常引起猪瘟，其防治疫苗研制备受关注。囊膜蛋白是一种有效的疫苗候选分子，本文综述伪狂犬病毒(rPRV-E2)、鸡痘病毒(rFPV-E0/E2)、Semliki森林病毒(rSFV-E2)、水疱性口炎病毒(rVSV-E2)、猪痘病毒(rSPV-E2)、腺病毒(rAdV-E2)、牛痘病毒(rVV-E2)、猪繁殖和呼吸综合征病毒(rPRRSV-E2)、杆状病毒(rBuV-E2)、猪霍乱沙门氏菌(rSc-E2)、鼠伤寒沙门氏菌(rSt-E2)、干酪乳杆菌(rLc-VP2-E290/E2-Tα1)、根癌农杆菌(rAt-E2)和酵母(rPP-E2)等载体介导的CSFV囊膜蛋白疫苗的构建及其免疫机制等方面研制现状。更多还原

【Abstract】 Classical swine fever virus(CSFV) is one type of pathogen agents casuing the classical swine fever, it recently becomes highlight to control this virus by use of the vaccine.The envolope protein is an attractive candidate molecule of vaccine, it’s outlined on the status in the research of conscruction and immune mechanism of vector＿based vaccine of envolope protein of CSFV,those vaccines include: Pseudorabies virus(rPRV-E2),fowlpox virus(rFPV-E0/E2),Semliki forest virus(rSFV-E2),Vesicular stomatitis virus(rVSV-E2),Swinepox virus(rSPV-E2),Adenovirus(rAdV-E2),Vaccinia virus(rVV-E2),Porcine reproductive and respiratory syndrome virus(rPRRSV-E2)and Buculovirus(rBuV-E2),Salmonella choleraesuis(rSc-E2),Salmonella typhimurium(rSt-E2),Lactobacillus casei(rLc-VP2-E290/E2-Tα1),Agrobacteria tumefaciens(rAt-E2)and Yeast(rPP-E2).更多还原