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显微手术与常规开颅切除手术治疗脑胶质瘤患者的效果及对术后并发症发生率的影响分析

Effect Analysis of Microsurgery and Routine Craniotomy on Glioma Patients and Incidence of Postoperative Complications

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【作者】 王维峰; 李明军; 李晓飞; 刘珂; 李泽昊;

【Author】 WANG Weifeng;LI Mingjun;LI Xiaofei;LIU Ke;LI Zehao;Jiamusi University The First Affiliated Hospital;

【通讯作者】 李明军;

【机构】 佳木斯大学附属第一医院;

【摘要】 目的 观察脑胶质瘤患者开展显微手术与常规开颅切除手术治疗的临床效果及其对术后并发症发生率的影响。方法 收集本院2020年8月-2022年5月脑胶质瘤病例72例,以不同治疗方案作为依据进行分组,将实施常规开颅切除手术的36例患者设定成对照组,将实施显微手术的36例患者设定成试验组,对比两组临床治疗效果、手术相关指标、术后并发症发生率、生活质量的差异。结果 在临床治疗总有效率的比较中,试验组更高,其与对照组差异明显(P<0.05);在两组手术时间、术中出血量、术后下床时间、住院时间等手术相关指标的比较中,试验组均优于对照组(P<0.05);在两组术后并发症发生率的比较中,试验组与对照组间存在的差异(P<0.05);在认知情况、躯体功能、社会适应、情绪功能等生活质量评分的比较中,验组均高于对照组(P<0.05)。结论 显微手术治疗脑胶质瘤的临床效果更理想,相较于常规开颅切除手术,其具有手术时间短、出血量少、并发症发生率低、恢复速度快等优点,可有效促进生活质量的提升,值得临床优先选择。

【Abstract】 Objective To observe clinical effect of microsurgery and routine craniotomy for glioma patients and analyze effect on incidence of postoperative complications. Methods The paper collected 72 cases of glioma patients in our hospital from August 2020 to May 2022, and divided them into groups based on different treatment plans. 36 cases in control group were treated with routine craniotomy surgery, and 36 cases in experimental group with microsurgery. Difference in clinical treatment effect, surgical related indicators, postoperative complication incidence and life quality were compared between two groups. Results Comparison showed, total effective rate of clinical treatment in experimental group was higher than control group, with significant difference(P<0.05). Surgical related indicators including surgical time, intraoperative bleeding, postoperative bedtime and length of stay in experimental group was better than control group, P<0.05. Difference of incidence of postoperative complications between experimental group and control group showed P< 0.05. Comparison of life quality scores difference, including cognitive status, physical function, social adaptation and emotional function, showed P< 0.05, those of experimental group were higher than control group. Conclusion Microsurgery can achieve more ideal clinical effect for glioma than routine craniotomy surgery, with advantages of shorter surgical time, less bleeding, lower incidence of complications and faster recovery,can improve life quality of patients effectively, which can be the first priority in clinical practice.

【基金】 黑龙江省卫生健康委科研课题《ATP1B3在恶性胶质瘤中的表达及其意义研究》(项目编号:2019-316)
  • 【分类号】R739.41
  • 【下载频次】3
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