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早期筛查胃肠道类癌代谢生化指标研究进展

Research Progress of Metabolic Biochemical Indicators for Early Screening of Gastrointestinal Carcinoid

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【作者】 文鑫华汪青春

【Author】 WEN Xinhua;WANG Qingchun;Traditional Chinese Medicine School, Southern Medical University;

【通讯作者】 汪青春;

【机构】 南方医科大学中医药学院

【摘要】 类癌(Carcinoid)为神经内分泌肿瘤,多见于消化道,病程发展缓慢。现时主要诊断胃肠道类癌的方法有实验室检查、影像学检查、内镜检查、病理学检查等,但因早期症状缺乏特异性,患者一般难以察觉,类癌早期诊断困难,因而错失治疗良机,故简便有效的筛查生化指标,有助于患者及早确诊和接受治疗。目前国内外研究有关胃肠道类癌的生化诊断检查可分为体内代谢物、组织细胞标志物、基因检测三类。

【Abstract】 Carcinoid is neuroendocrine tumor, mainly found in digestive tract with slow development. Currently, main methods for diagnosis of gastrointestinal carcinoid include laboratory examination, imaging examination, endoscopic examination, pathological examination, etc. However,due to lacking specificity of early symptoms, it is generally difficult to detect and diagnosis carcinoid early, and thus miss opportunity for treatment. Therefore, simple and effective screening of biochemical indicators may diagnose and treat patients as soon as possible. At present, biochemical diagnosis of gastrointestinal carcinoid can be divided into three categories: metabolites in vivo, tissue and cell markers, and gene detection.

  • 【分类号】R735
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