【摘要】 目的 通过meta分析明确Stanford A型主动脉夹层患者术后谵妄的危险因素。方法 计算机检索中国知网、万方、维普、中国生物医学文献数据库、Web of Science、Pub Med、Embase、Cochrane Library数据库，从建库至2023年3月有关Stanford A型主动脉夹层患者术后谵妄危险因素的文献，采用Rev Man 5.4软件对资料进行meta分析。结果共纳入27篇文献，总样本量为5 381例，术后发生谵妄的患者为1 734例，谵妄发生率为14.03%～50.4%。meta分析结果显示男性、年龄、深低温停循环时间、机械通气时间、ICU停留时间、脑血管病史、体外循环时间、肾功能不全、手术时间、术后使用镇静镇痛药、电解质紊乱及术前乳酸水平是Stanford A型主动脉夹层患者术后谵妄的独立危险因素。结论 医务人员可以结合上述12项危险因素及时对患者进行评估，以降低术后谵妄的发生率，从而促进患者的术后康复。更多还原

【Abstract】 Objective To identify the risk factors for postoperative delirium in patients with Stanford type A aortic dissection through meta-analysis. Methods Relevant literature on risk factors for postoperative delirium in patients with Stanford type A aortic dissection was retrieved from Chinese databases including CNKI, Wanfang, VIP, and CBM, as well as international databases like Web of Science, Pub Med, Embase, and the Cochrane Library from the establishment of the databases to March 2023. The data was analyzed using Rev Man 5.4 software. Results A total of 27 articles were included, with a total of5 381 patients as sample. Among them, 1 734 patients developed delirium after surgery, and the incidence of delirium ranged from 14.03% to 50.4%. The meta-analysis results showed that male patients, age, deep hypothermic circulatory arrest time, mechanical ventilation time, ICU stay time, history of cerebrovascular disease, cardiopulmonary bypass, renal insufficiency, operation time, use of sedatives and analgesics after surgery, electrolyte imbalance and preoperative lactate level were independent risk factors for postoperative delirium in patients with Stanford type A aortic dissection.Conclusion Healthcare professionals can timely evaluate patients based on the above 12 risk factors to reduce the incidence of postoperative delirium and promote the postoperative recovery of patients.更多还原