【摘要】 目的：探讨急性阑尾炎患者实施腹腔镜阑尾切除术治疗的临床效果。方法：从2020年1月～2022年1月来遂川县中医院就诊的急性阑尾炎患者中选取60例进行回顾性分析，按治疗方法不同分为两组，各30例。对照组行开腹阑尾切除术，观察组行腹腔镜阑尾切除术。于术后，比较两组临床相关指标、疼痛程度[视觉模拟评分法（VAS）]评分、炎症因子[C反应蛋白（CRP）、肿瘤坏死因子-ɑ（TNF-ɑ）、白细胞计数（WBC）]及并发症。结果：观察组手术时间（60.33±6.34）min、首次下床活动时间（1.77±0.46）d及住院时间（4.25±0.43）d均短于对照组；术后6h、12h及24h，观察组VAS评分分别为（3.12±0.36）分、（2.64±0.23）分、（2.15±0.24）分均低于对照组；术后两组炎症因子水平均升高，但观察组CRP(8.44±1.92)mg/L、TNF-ɑ（1.13±0.31）nmol/L、WBC(8.68±1.34)×10~9/L均低于对照组；观察组并发症发生率（3.33%）低于对照组（26.67%），差异均有统计学意义（P<0.05）。结论：腹腔镜阑尾切除术在针对急性阑尾炎患者的治疗中，效果显著，可改善临床相关指标，减轻术后疼痛及人体炎症反应，并降低并发症发生率。更多还原

【Abstract】 Objective: To explore the clinical effect of laparoscopic appendectomy for acute appendicitis. Methods: From January 2020 to January 2022, 60 patients with acute appendicitis in suichuan county Hospital of Traditional Chinese Medicine were selected and analyzed retrospectively. They were divided into two groups according to different treatment methods, with 30 cases in each group. The control group underwent open appendectomy, while the observation group underwent laparoscopic appendectomy. After operation, the clinical related indexes, pain degree [visual analogue scale(VAS)] score, inflammatory factors [C-reactive protein(CRP), tumor necrosis factor-ɑ(TNF-ɑ), white blood cell count(WBC)] and complications were compared between the two groups. Results: The operation time(60.33±6.34)min, the first time to get out of bed(1.77±0.46)d and the hospitalization time(4.25±0.43)d in the observation group were shorter than those in the control group. At 6 hours, 12 hours and 24 hours after operation, the VAS scores in the observation group were(3.12±0.36),(2.64±0.23) and(2.15±0.24) lower than those in the control group, respectively. After operation, the levels of inflammatory factors in both groups increased, but CRP(8.44±1.92)mg/L, TNF-ɑ(1.13±0.31) nmol/L and WBC(8.68± 1.34)×10~9/L in the observation group were lower than those in the control group. The incidence of complications in the observation group(3.33%) was lower than that in the control group(26.67%), and the difference was statistically significant(P<0.05). Conclusion: Laparoscopic appendectomy is effective in the treatment of acute appendicitis, which can improve clinical indexes, relieve postoperative pain and inflammatory reaction, and reduce the incidence of complications.更多还原