【摘要】 目的 评价湖北省急性弛缓性麻痹(Acute flaccid paralysis, AFP)病例监测系统运转质量和维持无脊髓灰质炎(脊灰)状态。方法 通过中国AFP监测信息报告管理系统收集湖北省2012-2021年AFP病例报告信息，进行描述性流行病学分析。结果 2012-2021年湖北省共报告<15岁儿童AFP病例1 773例，年均报告发病率为2.07/10万，各年报告发病率在1.28/10万-2.87/10万之间；AFP病例48h内调查率为99.15%,合格粪便标本采集率为89.68%。非脊灰肠道病毒分离率为10.49%(183/1 744)。检出脊灰疫苗相似株病例12例，其中Ⅰ型3例、Ⅱ型1例、Ⅲ型1例、混合型7例；未检出疫苗衍生脊灰病毒和脊灰野病毒。结论 湖北省2012-2021年AFP病例监测系统运转良好，继续维持无脊灰状态。更多还原

【Abstract】 Objective To evaluate the quality of acute flaccid paralysis(AFP) surveillance and to determine polio-free status in Hubei province.Methods We collected data on AFP cases reported to the National AFP Surveillance Information Management System during 2012-2021 in Hubei and conducted a descriptive epidemiological analysis.Results A total of 1 773 AFP cases <15 years of age were reported during 2012-2021 in Hubei, for a reported non-polio AFP incidence of 2.07 cases per 100 000 population. Annual incidences ranged from 1.28 to 2.87 per 100 000; 99.15% of AFP cases were investigated within 48 hours after reporting, and adequate stool specimens were collected from 89.68% of cases. The non-polio enterovirus positivity rate among AFP cases was 10.49%(183/1 744). Sabin-like strains were detected from 12 AFP cases, in which 3, 1, 1, and 7 cases were positive to poliovirus type Ⅰ, Ⅱ, Ⅲ, and mixed types, respectively. No vaccine-deprived polioviruses or wild polioviruses were found.Conclusions The AFP surveillance system ran well during 2012-2021, and polio-free status was continually maintained in Hubei.更多还原