【摘要】 目的 了解广东省广州市≥65岁社区老年人阿尔茨海默病（AD）的患病情况及其影响因素，为社区老年人的健康管理提供基础资料及参考依据。方法 于2021年9—10月采用随机整群抽样方法在广州市白云区钟落潭镇的13个社区抽取1 266名≥65岁常住社区老年人进行问卷调查和健康体检，并采用多因素非条件logistic回归模型分析该地区≥65岁社区老年人AD患病情况及影响因素。结果广州市1 266名≥65岁社区老年人中，患AD者87例，AD患病率为6.9%；多因素非条件logistic回归分析结果显示，年龄≥75岁、服用营养补充剂、日均睡眠时长>9 h、患糖尿病和心电图结果异常为广州市≥65岁社区居民AD患病的危险因素，初中及以上文化程度和使用义齿为广州市≥65岁社区居民AD患病的保护因素。结论 广州市≥65岁社区老年人的AD患病率较高，年龄、文化程度、是否服用营养补充剂、日均睡眠时长、是否使用义齿、是否患糖尿病和心电图结果为该地区≥65岁社区老年人AD患病的主要影响因素。更多还原

【Abstract】 Objective To investigate the prevalence and influencing factors of Alzheimer’s disease (AD) among community residents aged≥65 years in Guangzhou city for providing evidence to health management in community elderly.Methods Face-to-face interview and physical examination were conducted among 1 342 elderly residents (aged≥65 years) recruited with random cluster sampling from 13 communities in a district of Guangzhou city,Guangdong province during September–October 2021.A self-designed questionnaire,Mini-Mental State Examination (MMSE) and the Self-Care Ability Scale for Elderly People developed by domestic researchers were adopted in the survey.AD was diagnosed according to the criteria of International Classification of Diseases 10th Reversion (ICD-10) and International Working Group (IWG-2).Multivariate logistic regression model was used to analyze the influencing factors of AD.Results Among 1 266 participants with complete information,87 (6.9%) were diagnosed with AD.Multivariate logistic regression analysis showed that aged≥75 years,taking nutritional supplements,having daily sleep duration of more than 9 hours,suffering from diabetes and with abnormal electrocardiogram (ECG) were risk factors of AD;while,with the education of junior high school and above and having denture were protective factors against AD.Conclusion The prevalence rate of AD is high and mainly influenced by age,education,nutritional supplement intake,daily sleep duration,disease condition (diabetes and abnormal ECG),and denture use among 65 years old and elder community residents in Guangzhou city.更多还原