【摘要】 目的 回顾性分析阻塞性睡眠呼吸暂停患者睡眠效率与糖尿病发病率的相关性。方法 回顾性分析2002年10月1日-2021年9月30日某院呼吸科睡眠医学中心接受睡眠监测，并符合OSA诊断及纳入标准的2360名患者。所有患者根据睡眠效率比例不同分为≥85%,80%～84.9%和<80%3个组别，以多因素Logistic模型分析睡眠效率与DM之间的相关性。结果 在所有OSA患者中，校正相关因素后，与睡眠效率≥85%相比，睡眠效率<80%组其发生DM的概率明显升高(OR 1.476,95%CI 1.073～2.030,P=0.017)。年龄<60岁、男性以及BMI≥25kg/m~2患者中，校正相关因素后，睡眠效率<80%与DM的发生存在独立相关性(OR 1.619,95%CI 1.094～2.398,P=0.016;OR 1.712,95%CI 1.161～2.524,P=0.007;OR 1.500,95%CI 1.043～2.158,P=0.029)。结论 在OSA患者中，睡眠效率差与DM的发生存在显著的相关性，尤其在年轻男性及肥胖的人群中尤为显著。更多还原

【Abstract】 Objectives This study aims to retrospectively analyze the correlation between sleep efficiency and diabetes incidence in patients with obstructive sleep apnea syndrome(OSA). Methods From October 1, 2002 to September 30, 2021, 2,360 patients who underwent sleep monitoring in the Sleep Medicine Center of the Respiratory Department of a hospital and met the diagnosis and inclusion criteria for OSA were retrospectively analyzed. All patients were divided into groups of ≥85%, 80%～84.9%, and <80% according to the sleep efficiency ratio. The correlation between sleep efficiency and DM was analyzed by multivariate Logistic model.Results Among all OSA patients, after adjusting related factors, the probability of DM in the sleep efficiency <80% group was significantly higher compared with the sleep efficiency ≥85% group(OR 1.476, 95% CI 1.073-2.030, P=0.017). Among patients aged <60 years old, male, and BMI≥25kg/m~2, after adjusting related factors, the sleep efficiency <80% group was independently correlated with the occurrence of DM(OR 1.619,95% CI 1.094-2.398, P=0.016; OR 1.712, 95%CI 1.161～2.524, P=0.007; OR 1.500, 95%CI 1.043～2.158, P=0.029). Conclusions In OSA patients, poor sleep efficiency is significantly associated with the development of DM, especially in young men and obese people.更多还原