【摘要】 目的 探讨女性围绝经期骨质疏松状况及其危险因素。方法 回顾性分析2018年2月—2020年1月共175例围绝经期女性，根据骨密度-2.5SD为界线分成骨质疏松和非骨质疏松，分析骨质疏松状况，总结危险因素。结果 女性围绝经期骨质疏松者在基础知识、饮食运动、药物补充、诊疗知识及危险因素等因素方面评分显著低于非骨质疏松者，差异有统计学意义(P<0.05)。围绝经期骨质疏松共83例，发生率47.43%。影响女性围绝经期骨质疏松发生单危险因素有已绝经、文化程度低、家庭收入低(<3 000元/月)、BMI≤23 kg/m~2、未规律运动锻炼、久坐不动、未补充钙剂、存在不良饮食习惯及非骨质疏松者比较差异有统计学意义(P<0.05),而在居住地、婚姻日照时间、慢性病史、初潮年龄、哺乳时间、家族史及生育次数上比较差异无统计学意义(P>0.05)。经logistic回归分析，影响女性围绝经期骨质疏松独立危险因素有绝经(95%CI=0.746～2.451)、文化程度(95%CI=0.824～3.136)、家庭收入(95%CI=0.478～4.163)、BMI(95%CI=0.674～5.025)、运动锻炼(95%CI=0.724～3.896)、体力活(95%CI=0.568～4.268)、补充钙剂(95%CI=0.756～5.278)及饮食习惯(95%CI=0.614～5.784)。结论 围绝经期女性加强体力运动、保持合理体质量、改变不良生活习惯及增加钙剂摄入对预防围绝经期骨质疏松有重要价值。更多还原

【Abstract】 Objective To summarize the investigation and risk factors of perimenopausal osteoporosis in women.Methods A total of 175 perimenopausal women from February 2018 to January 2020 were retrospectively analyzed.According to bmd-2.5sd, they were divided into osteoporosis and non osteoporosis.Results(1) the scores of basic knowledge, diet and exercise, drug supplement, diagnosis and treatment knowledge and risk factors of female perimenopausal osteoporosis were significantly lower than those of non osteoporosis group(P<0.05).(2) There were 83 cases of perimenopausal osteoporosis, the incidence rate was 47.43%.The single risk factors of osteoporosis in perimenopausal women were menopause, low education level, low family income(< 3 000 yuan/month),BMI ≤ 23 kg/m~2,irregular exercise, sedentary, no calcium supplement, and unhealthy eating habits.The differences were statistically significant(P<0.05) compared with those without osteoporosis(P<0.05) There was no significant difference in menarche age, lactation time, family history and number of births(P>0.05).(3) Logistic regression analysis showed that menopause(P<0.05,95%CI=0.746-2.451),education level(P<0.05,95% CI=0.824-3.136),family income(P<0.05,95%CI=0.478-4.163),BMI(P<0.05,95% CI=0.674-5.025),exercise(P<0.05,95% CI=0.724-3.896),physical activity(P<0.05,95%CI=0.015,95% CI=0.568-4.268),calcium supplement(P<0.05,95% CI= 0.756-5.278),dietary habits(P<0.05,95% CI=0.614-5.784).Conclusion Strengthening physical exercise, maintaining reasonable weight, changing unhealthy living habits and increasing calcium intake are of great value in preventing perimenopausal osteoporosis.更多还原