【摘要】 目的 探讨经颅直流电刺激(tDCS)治疗卒中后中枢性疼痛(CPSP)的效果。方法 选取2019年3月至2022年3月广东省东莞市松山湖中心医院收治的CPSP患者66例，按照随机数字表法将其分为对照组及t DCS组，各33例。对照组予常规药物及康复治疗，tDCS组在对照组的基础上加用t DCS治疗，连续治疗2周。治疗前后比较两组视觉模拟评分法(VAS)、改良Barthel指数(MBI)及功能独立性评定(FIM)评分；比较两组疼痛疗效。结果 治疗过程中对照组因再发卒中脱落1例，最终纳入统计共65例。治疗后，两组VAS评分低于治疗前，且t DCS组低于对照组，差异有统计学意义(P<0.05)。治疗后，两组MBI评分及FIM评分高于治疗前，且t DCS组高于对照组，差异有统计学意义(P<0.05)。t DCS组疼痛疗效优于对照组，差异有统计学意义(P<0.05)。结论 t DCS有助于缓解CPSP程度，对疼痛疗效及患者日常生活活动能力有改善作用。更多还原

【Abstract】 Objective To investigate the effect of transcranial direct current stimulation(t DCS)in the treatment of central post-stroke pain(CPSP). Methods A total of 66 patients with CPSP admitted to Dongguan Songshan Lake Central Hospital,Guangdong Province from March 2019 to March 2022 were selected, and they were divided into control group and t DCS group according to the random number table method, with 33 cases in each group. Control group received conventional drugs and rehabilitation treatment, and t DCS group was treated with t DCS on the basis of control group, the treatment continued for two weeks. The scores of visual analogue scale(VAS), modified Barthel index(MBI), and function independence measure(FIM) of two groups were compared before and after treatment, and the pain efficacy of two groups was compared. Results In the control group, one case fell off due to recurrent stroke during treatment, and a total of 65 cases were included in the final statistics. After treatment, the VAS scores of two groups were lower than those before treatment, and t DCS group was lower than control group, and the differences were statistically significant(P<0.05). After treatment, MBI score and FIM score of two groups were higher than those before treatment, and t DCS group was higher than control group, and the differences were statistically significant(P <0.05). The pain effect of t DCS group was better than that of control group, and the difference was statistically significant(P<0.05). Conclusion t DCS can relieve the degree of CPSP, and improve the pain effect and the ability of daily living of patients.更多还原