【摘要】 糖尿病肾病（DN）为糖尿病的慢性并发症之一，极易导致肾衰竭，最后发展为终末期肾病。纤维蛋白原（FIB）是血栓形成前的重要物质，其水平升高提示凝血功能亢进。随着DN病情的进展，患者血栓形成风险增加，易并发心血管疾病，发生心血管事件是导致DN患者死亡的原因之一。本文就近年来对FIB与DN相关性的研究作一综述，旨在探讨FIB与DN关系的研究现状，阐述检测FIB对DN患者诊断、治疗的重要临床意义，以及为DN患者预防血栓形成、降低心血管事件发生风险提供支持。更多还原

【Abstract】 Diabetic nephropathy(DN) is one of the chronic complications of diabetes mellitus, which can easily lead to renal failure and finally develop into end-stage renal disease. Fibrinogen(FIB) is an important substance before thrombosis,and its elevated level indicates hypercoagulation. With the progression of DN, the risk of thrombosis increases and cardiovascular disease is easy to be complicated. The occurrence of cardiovascular events is one of the causes of death in DN patients. This paper reviews recent studies on the correlation between FIB and DN, aiming to explore the current research status of the relationship between FIB and DN, to elaborate the important clinical significance of detecting FIB in the diagnosis and treatment of DN patients, and to provide support for preventing thrombosis and reducing the risk of cardiovascular events in patients with DN.更多还原