【摘要】 目的 探讨颈动脉斑块超微血流成像(SMI)联合颈动脉彩色多普勒血流成像(CDFI)血流动力学参数对进展性缺血性脑卒中(PIS)的预测价值。方法 选取安徽省安庆市第一人民医院2020年1月至2022年3月收治的急性缺血性脑卒中患者147例,根据住院7 d内美国国立卫生研究院卒中量表评分变化情况将其分为PIS组(40例)与非PIS组(107例)。两组均进行颈动脉斑块SMI检查及颈动脉CDFI检查。收集相关临床资料及实验室检查指标分析PIS患者的影响因素;受试者操作特征曲线评估颈动脉斑块SMI联合CDFI血流动力学参数对PIS的预测价值。结果 两组糖尿病史、SMI分级、纤维蛋白原、阻力指数(RI)、收缩期峰值流速(PSV)、舒张末期流速(EDV)比较,差异有统计学意义(P<0.05)。糖尿病史、SMI分级为2级、RI、PSV、EDV为PIS的影响因素(P<0.05)。颈动脉斑块SMI联合颈动脉CDFI血流动力学参数预测PIS的曲线下面积高于各指标单独检测(P<0.05)。结论 颈动脉斑块SMI联合颈动脉CDFI血流动力学参数在PIS中具有较高的预测价值。更多还原

【Abstract】 Objective To investigate the predictive value of carotid plaque superb micro-vascular imaging(SMI) combined with carotid color Doppler flow imaging(CDFI) hemodynamic parameters in progressive ischemic stroke(PIS). Methods A total of 147 patients with acute ischemic stroke admitted to Anqing First People’s Hospital, Anhui Province from January 2020 to March 2022 were selected and they were divided into PIS group(40 cases) and non-PIS group(107 cases) according to the change of National Institutes of Health stroke scale score within seven days of hospitalization. Relevant clinical data and laboratory test indicators were collected, and the influencing factors of PIS in patients were analyzed. Receiver operating characteristic curve was used to evaluate the predictive value of carotid plaque SMI combined with carotid CDFI hemodynamic parameters in PIS.Results They were statistically significant in diabetes history, SMI grade, fibrinogen,resistance index(RI), peak systolic velocity(PSV), and end-diastolic velocity(EDV) between two groups(P<0.05). Diabetes history, SMI grade 2, RI, PSV, and EDV were the influencing factors of PIS(P<0.05). The area under the curve of carotid plaque SMI combined with carotid CDFI hemodynamic parameters for predicting PIS was higher than that of each index alone(P <0.05). Conclusion Carotid plaque SMI combined with carotid CDFI hemodynamic parameters has a high predictive value in PIS.更多还原