【摘要】 目的：构建全程管理随访系统，实现对胶质瘤患者的全程择优精细化管理。方法：基于临床科研一体化原则和客户机与服务器(C/S)模式，利用.NET平台、SQLite数据库以及C#语言开发，功能模块包括安全设置、查询检索、信息管理整合、信息导入导出和文件夹管理，构建胶质瘤患者全程管理随访系统。选取医院收治的188例高级别胶质瘤患者，按照就诊时间顺序将其分为对照组(88例)和观察组(100例)，对照组由随访团队给予常规随访，观察组在对照组随访基础上应用全程管理随访系统随访，比较两组患者的失访率和返院复查率。结果：观察组的失访率为2.00%，显著低于对照组(10.23%)；观察组返院复查率为92.00%，显著高于对照组(81.82%)，两组失访率和返院复查率比较差异有统计学意义(x~2=5.75,x~2=4.36;P<0.05)。结论：全程管理随访系统的应用能够有效提升临床和科研工作效率，辅助临床医生更好地完成胶质瘤患者全程择优精细化管理，提高患者治疗依从性，改善治疗效果。更多还原

【Abstract】 Objective: To construct a whole-process management and follow-up system to achieve whole-process optimal and refined management for glioma patients. Methods: Based on the principle of clinical scientific research integration and client and server(C/S) mode, using.NET platform, SQLite database and C# language development, setting up functional modules of security settings, query and retrieval, information management integration, information import and export and folder management,the whole-process management and follow-up system was constructed. A total of 188 patients with high-grade glioma admitted to the hospital were selected and divided into control group(88 cases) and observation group(100 cases) according to the time sequence of treatment. The control group was routinely followed up by the follow-up team. The observation group was followed up with the whole-course management and follow-up system on the basis of the control group. The loss of follow-up rate and returnto-hospital reexamination rate of between two groups were compared. Results: The loss of follow-up rate of the observation group was 2.00%, which was significantly lower than that of the control group(10.23%), the rate of return to hospital for reexamination was 92.00%, which was significantly higher than that of the control group(81.82%), the difference was statistically significant(x~2=5.75, x~2=4.36; P<0.05). Conclusion: The application of whole-process management and follow-up system can effectively improve the efficiency of clinical and scientific research, assist clinicians to better complete the whole-process optimal refined management of glioma patients, improve the treatment compliance of patients and the treatment effect.更多还原