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自拟糖胃方结合穴位热敷香包治疗糖尿病胃轻瘫的临床随机对照研究
Clinical Randomized Controlled Study of Self-designed Tangweifang Combined with Acupoint Heat Sachets for Diabetic Gastroparesis
【摘要】 目的 观察健脾活血疏肝解郁通络止痛方(自拟糖胃方)结合穴位热敷芳香醒胃香包治疗糖尿病胃轻瘫(diabetic gastroparesis, DGP)的临床疗效。方法 采用单中心随机对照研究方案,将64例DGP患者随机分为研究组和对照组,每组各32例。在西药控制血糖的基础上,研究组口服笔者医院协定处方,自拟“糖胃方”,1日3次+中药芳香醒胃香包热敷中脘穴位1日2次;对照组口服枸橼酸莫沙必利分散片5mg, 1日3次,均连续干预2周。观察两组治疗不同时间点的胃轻瘫主要症状指数量表(gastroparesis cardinal symptom index, GCSI)、体重指数(body mass index, BMI)及患者自我满意度评价。结果 两组GCSI临床症状评分、BMI均有改善,但研究组改善DGP症状、体质方面优于对照组,且研究组自我满意度优于对照组。1个月后随访,研究组的复发率为9.38%,对照组的复发率为18.75%,研究组复发率较低,再选择方案及交叉方案率优于对照组。结论 健脾活血疏肝解郁通络止痛方(自拟糖胃方)结合穴位热敷芳香醒胃中药香包治疗糖尿病胃轻瘫可以很好地改善患者临床症状,双向调节BMI,并减少临床复发,是值得临床推广运用的具有中医特色——内外合治的临床治疗方案。
【Abstract】 Objective To observe the clinical efficacy of Jianpihuoxueshuganjieyutongluozhitong fang(Self-designed Tangweifang) combined with acupoint heat aromatic wake stomach medicine sachets scheme in the treatment of diabetic gastroparesis(DGP). Methods Used single-center randomized controlled study, A total of 64 patients with DGP were randomly divided into study group and control group, 32 cases in each group. On the basis of western medicine to control blood glucose, the study group orally took the agreed prescription of West China Hospital, Sichuan University-self-designed ″Tangweifang″, 3 times a day + heated aromatic wake stomach medicine sachets to Zhongwan, 2 times a day; the control group took Mosapride citrate dispersible tablets 5mg orally, 3 times a day. Continuous intervention occurred for 2 weeks. the gastroparesis cardinal symptom index(GCSI), body mass index(BMI) and patient self-satisfaction evaluation of patients in the two groups were observed at different time points of treatment. Results The GCSI clinical symptom scores and BMI were improved in both groups, but the improvement of DGP symptoms and constitution in the study group was better than that in the control group, and the self-satisfaction in the study group was better than that in the control group. After 1month of follow-up, the recurrence rate in the study group was 9.38%, and that in the control group was 18.75%. The recurrence rate in the study group was lower, and the reselection and crossover rate were better than those in the control group. Conclusion Jianpihuoxueshuganjieyutongluozhitong fang(Self-designed Tangweifang) combined with acupoint heat aromatic wake stomach medicine sachets scheme in the treatment of DGP can improve the clinical symptoms, bidirectional regulation of BMI, and reduce clinical recurrence, which is worthy of clinical promotion and application with the traditional Chinese medicine characteristics-internal and external treatment of clinical treatment plan.
【Key words】 Diabetic gastroparesis; Tangweifang; Chinese medicine sachets; Randomized controlled study;
- 【文献出处】 医学研究杂志 ,Journal of Medical Research , 编辑部邮箱 ,2023年02期
- 【分类号】R259
- 【下载频次】22