【摘要】 目的：探讨妇科影像报告和数据系统（Gynecology Imaging Reporting and Data System,GI-RADS）分级与肿瘤标志物在小儿卵巢肿瘤良恶性鉴别中的价值。方法：回顾并分析100例小儿卵巢肿瘤的超声检查及糖类抗原（cancer antigen,CA）125、CA19-9检测结果，比较良恶性肿瘤标志物水平及超声特征。采用受试者工作特征（receiveroperating characteristic,ROC）曲线分析各项检查的诊断效能。结果：恶性组CA19-9、CA125高于良性组[（81.61±9.14）kU/L vs(19.55±4.85)kU/L,t=34.552;(68.42±6.15)kU/L vs (25.71±5.31)kU/L,t=23.747;P<0.05]。超声GI-RADS分级、CA19-9、CA125、联合诊断的准确度分别为86.00%、76.00%、72.00%、97.00%。同时，经ROC曲线分析，超声GIRADS分级、CA19-9、CA125及联合诊断的曲线下面积（areaundercurve,AUC）分别为0.833、0.689、0.667、0.939。结论：在诊断卵巢肿瘤良恶性时联合超声GI-RADS分级和肿瘤标志物，可提高诊断准确度。更多还原

【Abstract】 Objective:To explore the value of Gynecology Imaging Reporting and Data System(GI-RADS) grading and tumor markers in the differentiation of benign and malignant ovarian tumors in children.Methods:The ultrasonographic examination and the detection results of cancer antigen(CA) 125 and CA19-9 in 100 cases of ovarian tumors in children were retrospectively analyzed.The level of benign and malignant tumor markers and the ultrasonographic features were compared.At the same time,the efficacy of various diagnostic methods was analyzed by receiver operating characteristic(ROC) curve.Results:CA19-9 and CA125 in malignant group were higher than those in benign group [(81.61±9.14) kU/L vs(19.55±4.85) kU/L,t=34.552;(68.42±6.15) kU/L vs(25.71±5.31) kU/L,t=23.747;P<0.05].The diagnostic accuracy of GI-RADS grading,CA19-9,CA125,and combined diagnosis was 86.00%,76.00%,72.00%,97.00%.At the same time,by ROC curve analysis,the area under curve(AUC)of GI-RADS grading,CA19-9,CA125,and combined diagnosis in differential diagnosis of benign and malignant ovarian tumors were 0.833,0.689,0.667,and 0.939,respectively.Conclusion:Combining GI-RADS grading and tumor markers can improve the diagnostic accuracy in differentiating benign and malignant ovarian tumors.更多还原