【摘要】 目的 了解新型冠状病毒肺炎密接接触者的感染和发病情况，评价不同暴露水平下感染和发病风险。方法 采取回顾性研究方法，对辽宁省沈阳市2020年1月-2021年4月期间新型冠状病毒肺炎密切接触者的暴露和发病情况进行分析。结果 共纳入暴露三个等级的密切接触者28 915名，其中在5 719名密切接触者中发现64例阳性病例，总感染率为1.12%。密切接触者感染率在不同性别之间差异无统计学意义(χ~2=0.710,P>0.05)。不同年龄组间差异有统计学意义(χ~2=41.086,P<0.05),且感染率随着年龄的增加呈现上升趋势。不同社会关系的感染率差异有统计学意义(χ~2=134.017,P<0.05),家庭成员感染率最高(9.46%)。不同接触方式感染率差异有统计学意义(χ~2=33.115,P<0.05),生活接触及医疗接触的感染率高。结论 新型冠状病毒肺炎密切接触者感染与年龄、社会关系、接触方式均有关。更多还原

【Abstract】 Objective To understand the infection and morbidity of close contacts of COVID-19 cases, and evaluate the risk of infection and morbidity under different exposure levels. Methods A retrospective epidemiological method was used to describe and compare the exposure and morbidity of 28 915 close contacts of COVID-19 cases, whom were traced from January, 2020 to April, 2021. Results A total of 28 915 close contacts of 3 levels were included, of which 64 close contacts were found from 5 719 first-level close contacts, and the total infection rate was 1.12%.There was no significant difference in the infection rate of close contacts between sexes(χ~2=0.710,P>0.05).However, there were significant differences between age groups(χ~2=41.086,P<0.05),and the infection rate showed an upward trend with increasing age.The infection rate of different social relationships was significantly different(χ~2=134.017,P<0.05),and the infection rate of family members was the highest(9.46%).There was significant difference in the infection rate of different contact methods(χ~2=33.115,P<0.05),and the infection rate of life contact and medical contact was high. Conclusion The infection of close contacts in COVID-19 is associat with age, social relationship and mode of contact.更多还原