【摘要】 目的 掌握2020年南通市鼠类密度及8种病原体感染状况，评估鼠类传播疾病暴发和流行风险。方法 采用夹夜法和形态学鉴定监测鼠密度，采用实时荧光定量PCR检测鼠类致病性钩端螺旋体、莫氏立克次体、恙虫病东方体、巴尔通体、嗜吞噬细胞无形体和土拉弗朗西斯菌的感染状况；采用实时荧光定量RT-PCR检测鼠类汉坦病毒和新型布尼亚病毒的感染状况。结果 2020年南通市平均鼠密度为0.24%,优势种为小家鼠，鼠密度为0.16%。农村自然村鼠密度为0.34%,在3类生境中最高。鼠密度季节消长曲线呈单峰型，5月为高峰，峰值为0.40%。致病性钩端螺旋体检测阳性率为17.95%,其余7种病原体检测均为阴性。结论 2020年南通市鼠密度处于低水平，但鼠类存在致病性钩端螺旋体感染，对人群有致病风险，应加强相应监测。更多还原

【Abstract】 Objective To understand the rodent density and the infection status of eight pathogens in rodents, and to assess the risk of outbreaks and epidemics of rodent-borne diseases in Nantong City in 2020.Methods The rodent density was monitored by night trapping method and morphological identification, and the pathogens including pathogenic Leptospira,Rickettsia typhi,Orientia tsutsugamushi,Bartonella,Anaplasma phagocytophilum,and Francisella tularensis were detected by Real-time PCR,Hantavirus and new Bunyavirus were detected by Real-time RT-PCR.Results The average rodent density was 0.24% in Nantong in 2020.The dominant species was Mus musculus with rodent density of 0.16%.The rodent density in rural villages was 0.34%,the highest among the three types of habitats.A seasonal fluctuation unimodal curve of rodent density was observed and peaked at 0.40% in May.The positive test rate of pathogenic Leptospira was 17.95% and the remaining seven pathogens tested negative.Conclusion The rodent density is at a low level in Nantong City in 2020,but the existence of pathogenic Leptospira infection in rodents has posed a risk of transmission to humans, and corresponding surveillance should be strengthened.更多还原