【摘要】 目的 探讨针刺联合血府逐瘀汤加减治疗偏头痛的临床效果。方法 将100例偏头痛患者随机分为对照组(n=50,盐酸氟桂利嗪胶囊)和观察组(n=50,针刺联合血府逐瘀汤加减治疗)。比较两组的治疗效果。结果 随访结束时,观察组的偏头痛发作频次、头痛持续时间、主诉疼痛分级法(VRS)评分均低于对照组(P<0.05)。治疗后,观察组的大脑前动脉(ACA)、后动脉(PCA)、中动脉(MCA)平均血流速度均快于对照组(P<0.05)。治疗后,观察组的降钙素基因相关肽(CGRP)、环氧合酶-2(COX-2)、一氧化氮(NO)水平及匹兹堡睡眠质量指数(PSQI)、偏头痛特异生活质量问卷(MSQ)评分均低于对照组(P<0.05)。结论 针刺联合血府逐瘀汤加减治疗偏头痛的效果良好。更多还原

【Abstract】 Objective To explore the clinical effect of acupuncture combined with modified Xuefu Zhuyu decoction in the treatment of migraine. Methods One hundred patients with migraine were randomly divided into control group(n=50,flunarizine hydrochloride capsule) and observation group(n =50, acupuncture combined with modified Xuefu Zhuyu decoction). The therapeutic effects of the two groups were compared. Results At the end of follow-up, the scores of frequency of migraine attack, duration of headache and Verbal Rating Scale(VRS) in the observation group were lower than those in the control group(P<0.05). After treatment, the average blood flow velocities of the anterior cerebral artery(ACA),posterior cerebral artery(PCA) and middle cerebral artery(MCA) in the observation group were faster than those in the control group(P<0.05). After treatment, the levels of calcitonin gene-related peptide(CGRP), cyclooxygenase-2(COX-2),nitric oxide(NO) and Pittsburgh Sleep Quality Index(PSQI), Migraine Specific Quality of Life Questionnaire(MSQ) scores in the observation group were lower than those in the control group(P <0.05). Conclusion Acupuncture combined with modified Xuefu Zhuyu decoction in the treatment of migraine has a good effect.更多还原