【摘要】 目的：分析肠内营养支持在头颈部肿瘤放疗患者中的应用效果。方法：选择2020年6月—2022年6月滨州医学院附属医院肿瘤科收治的130例头颈部肿瘤放疗患者作为研究对象。根据电脑随机数表法分为观察组和对照组，各65例。对照组予以常规营养护理，观察组予以肠内营养支持。比较两组的近期疗效、营养状态、放射性口腔黏膜炎发生情况、自我效能感及生存质量评分。结果：观察组客观有效率为80.00%，高于对照组的76.92%，但两组间比较，差异无统计学意义（P>0.05）。干预前，两组营养状态各项指标比较，差异无统计学意义（P>0.05）；干预后，对照组体重指数、血红蛋白、白蛋白、淋巴细胞低于干预前，患者主观整体评估量表（PG-SGA）评分高于干预前，差异有统计学意义（P<0.05），而观察组各项指标与干预前比较，差异无统计学意义（P>0.05），干预后，观察组体重指数、血红蛋白、白蛋白、淋巴细胞均高于对照组，PG-SGA评分低于对照组，差异有统计学意义（P<0.05）。观察组放射性口腔黏膜炎发生率为23.08%，低于对照组的40.00%，差异有统计学意义（P<0.05）。干预前，两组中文版癌症自我效能评估量表评分、中文版癌症患者生命质量通用量表（FACT-G）评分比较，差异无统计学意义（P>0.05）；干预后，两组中文版癌症自我效能评估量表评分、FACT-G评分均高于干预前，且观察组高于对照组，差异有统计学意义（P<0.05）。结论：肠内营养支持应用在头颈部肿瘤放疗患者中可取得显著效果，不仅能保证近期疗效，改善营养状态，预防放射性口腔黏膜炎，而且还能促进患者自我效能感及生存质量进一步提高。更多还原

【Abstract】 Objective: To analyze the effect of enteral nutrition support in patients with radiotherapy for head and neck tumors.Method: A total of 130 patients with radiotherapy for head and neck tumor admitted to the Department of Oncology of Affiliated Hospital of Binzhou Medical College from June 2020 to June 2022 were selected as the study objects. According to the method of computer random number table, they were divided into observation group and control group, with 65 cases in each group. The control group was given routine nutrition nursing, and the observation group was given enteral nutrition support. The short-term efficacy, nutritional status, incidence of radiation oral mucositis, self-efficacy and quality of life score of the two groups were compared. Result: The objective effective rate of the observation group was 80.00%, which was higher than 76.92% of the control group, but there was no significant difference between the two groups(P>0.05). Before intervention, there were no significant differences in indexes of nutritional status between the two groups(P>0.05). After intervention, the body mass index, hemoglobin, albumin and lymphocyte of the control group were lower than those before intervention, and the patient-generated subjective global assessment(PG-SGA) score of the control group was higher than that before intervention, the differences were statistically significant(P<0.05), while there was no statistical significance in all indicators of the observation group compared with before intervention(P>0.05). After intervention, the body mass index, hemoglobin, albumin and lymphocyte in observation group were higher than those in control group, while PG-SGA score was lower than that in control group, the differences were statistically significant(P<0.05). The incidence of radiation oral mucositis in the observation group was 23.08%, which was lower than 40.00% in the control group, and the difference was statistically significant(P<0.05). Before intervention, there were no significant differences between the two groups in Chinese version of cancer self-efficacy assessment scale and Chinese version of functional assessment of cancer therapy-general(FACT-G)(P>0.05). After intervention, the Chinese version of the cancer self-efficacy assessment scale score and FACT-G score in both groups were higher than those before intervention, and the observation group were higher than those in the control group, the differences were statistically significant(P<0.05).Conclusion: The application of enteral nutrition support in patients with radiotherapy for head and neck tumor can achieve significant results, which can not only ensure short-term efficacy, improve nutritional status, prevent radiation oral mucositis, but also promote the further improvement of patients’ self-efficacy and quality of life.更多还原