【摘要】 目的 了解肝吸虫病患者发生并发症的影响因素。方法 回顾性分析2015年1月1日至2019年12月31日在右江民族医学院附属医院、百色市人民医院首次就诊并明确诊断为肝吸虫病的175例患者资料，根据是否存在并发症分为并发症组与无并发症组，收集并比较两组患者的一般资料和血脂检查指标，采用logistic回归分析影响肝吸虫病患者发生并发症的因素。结果 两组患者在性别、年龄、食用鱼生史、户籍居住地、职业、饮酒史、BMI、TC、TG、LDL-C、HDL-C上的差异有统计学意义(P<0.05),而在民族、文化程度上的差异无统计学意义(P>0.05);多因素logistic回归分析结果显示，年龄≥66岁(OR=10.927,95%CI:1.787～66.805)、有饮酒史(OR=3.535,95%CI:1.097～11.390)、BMI≥24 kg/m~2(OR=3.898,95%CI:1.408～10.793)、TC>6.2 mmol/L(OR=2.929,95%CI:1.016～8.447)、TG>1.8 mmol/L(OR=4.890,95%CI:1.805～13.248)、HDL-C<1.0 mmol/L(OR=5.533,95%CI:1.837～16.660)是肝吸虫病患者发生并发症的危险因素。结论 肝吸虫病患者并发症的发生可能与年龄、饮酒史、BMI、TC、TG及HDL-C存在密切关联，在临床诊治过程中应加以重视，避免该病并发症的发生发展。更多还原

【Abstract】 Objective To understand the influencing factors of complications in patients with clonorchiasis sinensis. Methods A retrospective analysis was conducted on the data of 175 patients who first visited and were diagnosed with clonorchiasis sinensis in the Affiliated Hospital of Youjiang Medical University for Nationalities and the People’s Hospital of Baise from January 1, 2015 to December 31, 2019. All patients were divided into complication group and non complication group based on the presence of complications. And then, general information and blood lipid test indicators of the two groups were collected and compared, and factors affecting the complications of patients with clonorchiasis sinensis were analyzed by logistic regression. Results There were statistically significant differences in gender, age, history of eating raw fish, registered residence, occupation, drinking history, BMI, TC, TG, LDL-C and HDL-C between the two groups(P<0.05), but there were no statistically significant differences in nation and education level(P>0.05). Multivariate logistic regression analysis showed that, age ≥ 66 years old(OR=10.927, 95% CI: 1.787-66.805), drinking history(OR=3.535, 95% CI: 1.097-11.390), BMI≥24 kg/m~2(OR=3.898, 95% CI: 1.408-10.793), TC>6.2 mmol/L(OR=2.929, 95% CI: 1.016-8.447), TG>1.8 mmol/L(OR=4.890, 95% CI: 1.805-13.248), HDL-C<1.0 mmol/L(OR=5.533, 95% CI: 1.837-16.660) were risk factors for complications in patients with clonorchiasis sinensis. Conclusion The occurrence of complications in patients with clonorchiasis sinensis may be closely related to age, drinking history, BMI, TC, TG and HDL-C. Attention should be paid in the process of clinical diagnosis and treatment to avoid the occurrence and development of complications of the disease.更多还原