【摘要】 目的 探讨双腔气管插管联合低CO₂压力在胸腔镜食管癌根治术中的应用效果。方法 64例食管癌根治术患者随机分为两组。观察组采用双腔气管插管，术中CO₂压力控制在3～5 mm Hg；对照组采用单腔气管插管，术中CO₂压力控制在8～10 mm Hg。比较两组的手术相关指标、血气指标及血流动力学指标。结果 观察组的手术时间、意识恢复时间及拔管时间均短于对照组（P<0.05）。气胸建立1 h及气胸建立2 h时，观察组的p H、PaO₂、MAP均高于对照组，PaCO₂、HR均低于对照组（P<0.05）。结论 双腔气管插管联合低CO₂压力可提高胸腔镜食管癌根治术的安全性，稳定患者血气指标和血流动力学指标。更多还原

【Abstract】 Objective To explore the application effect of double lumen endotracheal intubation combined with low CO₂ pressure in thoracoscopic radical resection of esophageal cancer.Methods 64 patients with thoracoscopic radical resection of esophageal cancer were randomly divided into two groups.The observation group received double lumen endotracheal intubation,and intraoperative CO₂ pressure was controlled at 3～5 mm Hg.The control group received single lumen endotracheal intubation,and the intraoperative CO₂ pressure was controlled at 8～10 mm Hg.The operation related indicators,blood gas indicators and hemodynamic indicators of the two groups were compared.Results The operation time,consciousness recovery time and extubation time of the observation group were shorter than those of the control group （P<0.05）.At 1 h after pneumothorax establishment and at 2 h after pneumothorax establishment,pH,PaO₂ and MAP of the observation group were higher than those of the control group,and PaCO₂ and HR were lower than those of the control group （P<0.05）Conclusions Double lumen endotracheal intubation combined with low CO₂ pressure can improve the safety of thoracoscopic radical resection of esophageal cancer,and stabilize the blood gas and hemodynamic indicators of patients.更多还原