【摘要】 阻塞性睡眠呼吸暂停(OSA)可引起机体多器官多系统的并发症，并与眼表疾病也具有一定关联。干眼(DE)是目前临床上最常见的眼表疾病，不同程度地影响着视觉相关的生活和工作。最近的研究揭示了OSA与DE之间的潜在关系，OSA可通过氧化应激、炎症、节律紊乱等一系列机制诱导DE的发生，OSA患者合并DE后将以一种新形式从整体上深刻影响着患者的睡眠健康、心境障碍和生活质量。然而，目前尚缺乏对OSA与DE共病的系统认识，导致临床上对OSA患者相关DE的筛查与诊治不足。本研究就OSA与DE的关系进行综述，以期提高临床医师在治疗OSA过程中对DE的诊断与管理意识。更多还原

【Abstract】 Obstructive sleep apnea(OSA) can lead to complications in various systems and organs of the body. Dry eye(DE), the most common ocular surface disease in clinical practice, affects visual-related daily activities and work in varying degrees. Recent studies have revealed a potential relationship between OSA and DE. OSA can induce DE through a series of mechanisms such as oxidative stress, inflammation, rhythm disorder and so on, and the combination of OSA and DE may profoundly affect the sleep health, mood disorders, and quality of life of patients in a new form overall. However, there is still a lack of systematic understanding of the comorbidity of OSA and DE, resulting in insufficient screening, diagnosis and treatment of OSA related DE in clinical practice. This paper provided a review of the relationship between OSA and DE to raise awareness among clinicians of the diagnosis and management of DE during OSA treatment.更多还原