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一例患者经颈静脉肝内门体分流术术中碘克沙醇致过敏性休克后顺利完成手术及文献分析(英文)
A case of anaphylactic shock caused by iodixanol during transjugular intrahepatic portosystemic shunt and literature analysis
【摘要】 河北医科大学第二医院消化内科收治一例68岁患者,局部麻醉下行经颈静脉肝内门体分流术(transjugular intrahepatic portosystem shunt, TIPS),使用碘克沙醇注射液高压造影, 15分钟后患者出现血压下降、皮肤瘙痒等症状,考虑患者出现过敏性休克,立即给予抗过敏、抗休克等急救治疗措施。患者生命体征指标逐渐恢复,过敏性休克症状逐渐消失,手术继续且顺利完成,无并发症发生。现就此例经颈静脉肝内门体分流术术中碘克沙醇注射液致过敏性休克患者的抢救措施及治疗情况进行分析,旨在加强临床安全使用碘克沙醇的用药意识。当患者使用碘克沙醇注射液造影时,短时间内出现血压下降,皮肤瘙痒等问题时,可能发生了过敏性休克。术中应严密观察患者的病情,及时发现过敏症状并及时进行有效处理,是抢救过敏性休克的关键。
【Abstract】 A 68-year-old patient was admitted to the Department of Gastroenterology at the Second Hospital of Hebei Medical University and underwent a transjugular intrahepatic portosystemic shunt (TIPS) under local anesthesia using iodixanol injection for high pressure imaging. After 15 min, the patient developed symptoms, such as a drop in blood pressure and skin itching, indicating anaphylactic shock. We promptly administered emergency measures, including antiallergic and anti-shock treatment. The patient’s vital signs gradually recovered, and the symptoms of anaphylactic shock disappeared. Ultimately, the operation was successfully completed without any complications. This article analyzed the rescue measures and treatment of a patient who experienced anaphylactic shock due to an iodixanol injection during TIPS. The purpose was to increase awareness of the safe use of iodixanol. When iodixanol is used for contrast, a patient may experience a drop in blood pressure and skin itching within a short period of time, potentially leading to anaphylactic shock. During the operation, it is crucial to closely monitor the patient’s condition and promptly recognize allergic symptoms for effective treatment. This is the key to rescuing a patient experiencing anaphylactic shock.
【Key words】 Transjugular intrahepatic portosystemic shunt; Iodixanol injection; Anaphylactic shock; Rescue measures;
- 【文献出处】 Journal of Chinese Pharmaceutical Sciences ,中国药学(英文版) , 编辑部邮箱 ,2023年08期
- 【分类号】R969
- 【下载频次】11