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低温等离子系统联合腺样体扁桃体切除术在阻塞性睡眠呼吸暂停低通气综合征患儿中的应用分析

Application of low-temperature plasma system combined with adenotonsillectomy in children with obstructive sleep apnea-hypopnea syndrome

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【作者】 张群陈明清

【Author】 ZHANG Qun;CHEN Mingqing;Otolaryngology-Head and Neck Surgery,Shangqiu Third People’s Hospital;

【机构】 商丘市第三人民医院耳鼻咽喉-头颈外科

【摘要】 目的 探讨低温等离子(LTP)系统联合腺样体扁桃体切除术在阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患儿治疗中的应用效果,为治疗OSAHS患儿提供参考依据。方法 选取2020年1月—2022年1月本院收治的72例OSAHS患儿,按随机数字表法分为2组,各36例。对照组予以传统腺样体扁桃体切除术治疗,观察组予以LTP系统联合腺样体扁桃体切除术治疗,随访3个月。比较2组围术期相关指标、通气功能、睡眠质量、免疫功能、应激反应及并发症发生情况。结果 观察组术后呼吸紊乱指数为(10.15±1.43),低于对照组的(14.32±2.21),最低血氧饱和度为(80.24±6.62)%、平均血氧饱和度为(92.25±7.25)%、QSQ评分为(189.62±12.14)分,分别高于对照组的(75.08±6.55)%、(88.79±7.12)%、(175.36±11.58)分,最长呼吸暂停时间为(18.25±2.18)s,短于对照组的(22.37±2.24)s(t=9.505、3.325、2.043、7.909、5.100,P均<0.05);观察组术后CD3~+为(66.89±5.75)%、CD4+为(35.25±3.31)%、CD4~+/CD8~+为(1.46±0.28),分别高于对照组的(62.41±5.52)%、(31.25±3.24)%、(1.12±0.25),CD8+为(24.15±2.75)%,低于对照组的(27.89±2.86)%(t=3.372、5.182、5.656、5.435,P均<0.001)。结论 LTP系统联合腺样体扁桃体切除术治疗OSAHS效果更佳,能减轻机体创伤,改善患儿通气功能及睡眠质量,且对免疫功能影响小,并发症少,安全可靠。

【Abstract】 Objective To explore the application effect of low-temperature plasma (LTP) system combined with adenotonsillectomy in the treatment of children with obstructive sleep apnea-hypopnea syndrome (OSAHS),so as to provide a reference for clinical treatment of children with OSAHS.Methods A total of 72 children with OSAHS admitted to our hospital from January 2020 to January 2022 were enrolled and divided into two groups with 36 cases in each group according to the random number table method.The control group was treated with traditional adenotonsillectomy,and the observation group was treated with an LTP system combined with adenotonsillectomy,and the follow-up was 3 months.The two groups were compared with perioperative indexes,ventilation function,sleep quality,immune function,stress response,and complications.ResultsThe postoperative respiratory disturbance index in the observation group was (10.15±1.43),lower than that in the control group:(14.32±2.21).The lowest oxygen saturation was (80.24±6.62)%,the average oxygen saturation was(92.25±7.25)%,and the QSQ score was (189.62±12.14) points in the observation group,which were higher than those of the control group:(75.08±6.55)%,(88.79±7.12)%,and (175.36±11.58) points respectively.The longest apnea time was (18.25±2.18) s in the observation group,which was shorter than that in the control group:(22.37±2.24) s (t=9.505,3.325,2.043,7.909,5.100,all P<0.05).In the observation group,the postoperative CD3~+%,CD4~+%,and CD4~+/CD8~+were (66.89±5.75)%,(35.25±3.31)%,and (1.46±0.28) respectively,which were higher than those of the control group:(62.41±5.52)%,(31.25±3.24)%,and (1.12±0.25) respectively,but CD8~+in the observation group was (24.15±2.75)%,lower than that in the control group:(27.89±2.86)%(t=3.372,5.182,5.656,5.435,all P<0.001).Conclusion LTP system combined with adenotonsillectomy is more effective in the treatment of OSAHS,which can reduce trauma,improve the ventilation function and sleep quali-ty of children,has little impact on immune function,has fewer complications,and is safe and reliable.

  • 【文献出处】 中国校医 ,Chinese Journal of School Doctor , 编辑部邮箱 ,2023年05期
  • 【分类号】R766.9
  • 【下载频次】18
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