【摘要】 目的 探讨影响青少年抑郁症患者出现非自杀性自伤行为的危险因素。方法 收集西安交通大学第一附属医院291例抑郁症患者的一般临床资料，收集贫血因子三项、血脂八项、糖化血红蛋白，超敏C反应蛋白、尿酸水平等生化指标，根据是否出现非自杀性自伤行为分为有自伤行为组(163例)和无自伤行为组(128例)。采用Logistic回归分析方法对各相关因素进行分析。结果 与无自伤行为组比较，有自伤行为组患者伴有更多的创伤史及诱发因素，差异有统计学意义(P<0.05);与无自伤行为组相比，有自伤行为组患者铁蛋白水平明显升高(P<0.05);有自伤行为组患者HDL-C水平低于无自伤行为组，差异有统计学意义(P<0.05);Logistic回归分析提示，铁蛋白是青少年抑郁症患者出现非自杀性自伤行为的危险因素(OR=1.014,95%CI:1.004～1.025,P=0.006);HDL-C是青少年抑郁症患者出现非自杀性自伤行为的保护因素(OR=0.204,95%CI:0.995～1.027,P=0.011)。结论 社会心理因素是青少年抑郁症患者出现非自杀性自伤行为的重要影响因素，铁蛋白、HDL-C有望成为青少年抑郁症患者出现非自杀性自伤行为的潜在预测指标。更多还原

【Abstract】 Objective To explore the risk factors of non-suicidal self-injury(NSSI) behavior in adolescents with depression.Methods Collect the general clinical data of 291 patients with depression, biochemical indicators include three factors of anemia, blood lipid eight, glycosylated hemoglobin, hypersensitive C-reactive protein(hs-CRP), uric acid level, etc. According to the occurrence of NSSI, the patients were divided into two groups: group with NSSI(163 cases) and group without NSSI(128 cases). Chi-square test was used to analyze the enumeration data, T test was used to analyze the measurement data, and Logistic regression analysis was used to analyze the relevant factors.Results Adolescent depression patients with traumatic experience, inducement, high ferritin level and low HDL-C level were more likely to have NSSI.Conclusion Social-psychological factors are important influencing factors for NSSI in adolescent patients with depression. Ferritin and HDL-C are expected to be potential predictors for NSSI in adolescent patients with depression.更多还原