【摘要】 目的 观察氢溴酸樟柳碱治疗急性后循环脑梗死（posterior circulation cerebral infarction,PCCI）的临床效果。方法 选取2021年6月—2022年12月泉州市第一医院收治的急性PCCI患者100例作为回顾性研究对象，以治疗方案不同分为对照组与研究组，各50例。对照组接受常规治疗，研究组采用常规治疗+氢溴酸樟柳碱治疗。对比两组的治疗效果及安全性。结果 治疗14 d，与对照组相比，研究组患者大脑后动脉、椎动脉、基底动脉收缩期血流速度较高、阻力指数较低，炎症因子水平较低，神经缺损评分较低，日常生活活动能力评分较高（P <0.05）。两组药物相关不良反应情况比较，差异无统计学意义（P> 0.05）。结论 急性PCCI常规治疗同时增加使用氢溴酸樟柳碱，可促进患者脑血流状态及炎性反应得到良好改善，积极改善预后情况，且用药方案安全性表现优异。更多还原

【Abstract】 Objective To observe the clinical effect of anisodine hydrobromide on acute posterior circulation cerebral infarction(PCCI). Methods A total of 100 patients with acute PCCI admitted to Quanzhou First Hospital were taken as retrospective research objects, and the enrollment time was limited from June 2021 to December 2022. Taking different treatment schemes as grouping criteria, 50 patients who received routine treatment were included in the control group, and 50 patients who received routine treatment plus anisodine hydrobromide were included in the study group, and the therapeutic effect and safety were compared. Results After 14days of treatment, compared with the control group, the patients in the study group had higher systolic blood flow velocity, lower resistance index, lower inflammatory factor level, lower nerve defect score and higher activity of daily living score(P < 0.05). There was no statistical difference in drug-related adverse reactions between the two groups(P > 0.05). Conclusion The routine treatment of acute PCCI combined with the use of anisodine hydrobromide can improve the cerebral blood flow and inflammatory reaction of patients, and positively improve the prognosis. The safety of the medication scheme is excellent.更多还原