【摘要】 铁死亡是一种铁依赖性的新型细胞死亡形式，已被证实在多种疾病的病理生理过程中发挥重要作用。本文总结了铁死亡的主要代谢途径，包括铁代谢途径、脂代谢途径和经典的GSH/GPX4代谢途径等。同时本文探讨了铁死亡代谢对溃疡性结肠炎的调控作用和机制，旨在为溃疡性结肠炎的治疗提供新的思路和研究方向。更多还原

【Abstract】 Ferroptosis is a novel form of cell death with iron dependence, which has been confirmed to play an important role in the pathophysiology of various diseases. This review summarized the main metabolic pathways of ferroptosis, including iron metabolic pathway, lipid metabolic pathway and the classic GSH/GPX4 metabolic pathway. At the same time, this review discussed the regulatory effect and mechanism of ferroptosis metabolism on ulcerative colitis,aiming to provide new ideas and research directions for the treatment of ulcerative colitis.更多还原