【摘要】 目的:对哈尔滨市适龄在校儿童口腔健康综合干预项目预防第一恒磨牙龋病的经济性进行评价,为进一步扩大项目覆盖范围提供经济学证据。方法:基于哈尔滨市适龄在校儿童口腔健康综合干预项目资料,建立Markov模型。结果:封闭组和空白组发生龋齿数量分别为29 909颗牙和83 533颗牙,患龋率分别为8.92%和24.92%;封闭组的患龋率降低了16.00%;封闭组相对于空白组而言,ICER和ICUR分别为-33.69元/避免一颗龋齿发生和-36.88元/QATY,成本-效果和成本-效用分析均显示封闭组为绝对优势策略。敏感性分析显示模型稳定性较好。结论:对适龄儿童的第一恒磨牙进行窝沟封闭预防龋齿具有极佳的经济性,建议进一步扩大项目的覆盖范围。更多还原

【Abstract】 Objective:To evaluate the economic effectiveness of the Harbin school-age Integrated Oral Health Intervention Program for the prevention of dental caries in first permanent molars,and to provide economic evidence for further expansion of the program coverage.Methods:A Markov model was established based on the data from the comprehensive oral health intervention program for school-age children in Harbin.Results:The number of dental caries was 29 909 in the sealing group and 83 533 in the blank group,and the caries prevalence were 8.92% and 24.92%,respectively,and the caries prevalence was reduced by 16.00% in the sealing group.Compared with the blank group,the ICER and ICUR of the sealing group were-33.69 yuan/a caries avoided and-36.88 yuan/QATY,respectively.The cost-effectiveness and cost-utility analysis showed that the sealing group was an absolute superior strategy.Sensitivity analysis showed that the model was stable.Conclusion:Vulcanization of the first permanent molars of school-age children for the prevention of dental caries is extremely economical and further expansion of the programme is recommended.更多还原