【摘要】 目的 探讨糖尿病诊断中糖化血红蛋白与血清C肽单一或联合检验的作用。方法 选取2023年1—6月泰州市第四人民医院收治的糖尿病患者116例为研究对象，并选取同时期健康体检人员116名，分别为观察组和对照组。比较两组血糖、糖化血红蛋白与血清C肽水平等指标。结果 观察组糖化血红蛋白较对照组高，血清C肽水平较对照组低，差异有统计学意义（P均<0.05）；联合检测诊断灵敏度（93.97%）、特异度（99.14%）及准确率（96.55%）均较单一糖化血红蛋白（78.45%、88.79%、83.62%）及血清C肽（76.72%、87.93%、82.33%）高，差异有统计学意义（P均<0.05）。结论 糖尿病诊断中糖化血红蛋白与血清C肽联合检测有助于提高检出率，便于临床结合检测结果改善患者预后。更多还原

【Abstract】 Objective To investigate the role of single or combined test of glycosylated hemoglobin and serum Cpeptide in the diagnosis of diabetes mellitus. Methods A total of 116 patients with diabetes admitted to Taizhou Fourth People’s Hospital from January to June 2023 were selected. As the study subjects, and 116 healthy physical examination personnel during the same period were selected. As the observation group and the control group, respectively. The blood glucose, glycosylated hemoglobin and serum C-peptide levels were compared between the two groups. Results The levels of HbA1c was higher and serum C-peptide was lower in the observation group than those in the control group, and the differences were statistically significant(both P<0.05). The diagnostic sensitivity(93.97%), specificity(99.14%) and accuracy(96.55%) were higher than those of single HbA1c(78.45%, 88.79%,83.62%) and serum C-peptide(76.72%, 87.93%, 82.33%), and the differences were statistically significant(all P<0.05). Conclusion The combined detection of glycosylated hemoglobin and serum C-peptide in the diagnosis of diabetes can improve the detection rate, facilitate the clinical combination of detection results to improve the prognosis of patients.更多还原