【摘要】 高度近视在年轻人群中越来越常见，可分为单纯性高度近视和病理性高度近视。后者在世界范围内是导致失明的重要因素，其中东亚国家尤甚。随着光学相干断层扫描血管成像(optical coherence tomography angiography, OCTA)的发展和应用，这种方便、无创、穿透性强的眼底成像技术使我们对高度近视的病理生理机制认识有了很大的提高。在定量分析方面，OCTA可用于评估不同程度近视患者的视网膜和脉络膜的血管灌注和厚度，以监测近视性黄斑病变的病程和评价眼底手术治疗的效果。定性分析方面，OCTA可以观察近视眼底形态学变化，例如近视性牵引性黄斑病变手术后的解剖复位情况，以及抗血管内皮生长因子(anti-vascular endothelial growth factor, anti-VEGF)治疗近视性脉络膜新生血管(myopic choroidal neovascularization, mCNV)后的变化。该文就OCTA在高度近视领域的应用研究现状和进展作一综述。更多还原

【Abstract】 Myopia is becoming more prevalent in younger generations, and it can be classified into simple myopia and pathological myopia.The latter is a significant contributor to social blindness, particularly in East Asian nations.With the development of optical coherence tomography angiography(OCTA)as a convenient, noninvasive, and penetrating fundus imaging technology, our comprehension of the pathophysiology of myopia has significantly increased.For quantitative analysis, OCTA can be used to assess the vascular perfusion and thickness of retina as well as choroid at various degrees of myopia in order to monitor the course of myopia macular degeneration and to evaluate the efficacy of surgical therapy.And for qualitative evaluation, OCTA enables the observation of morphological changes, such as the anatomical recovery of myopic traction maculopathy after surgery and variations in choroidal neovascularization following anti-VEGF treatment.This review summarizes the current status and progress of OCTA application in myopia.更多还原