【摘要】 目的 分析厦门市8～10岁儿童甲状腺容积影响因素，为科学评价碘缺乏病防治效果，调整甲状腺容积评价指标提供科学依据。方法 厦门市六区按东、西、南、北、中5个片区各抽取1所小学的8～10岁非寄宿学生，采集1次随机尿样、家中盐样、甲状腺容积、身高、体重。结果 共抽取厦门市8～10岁儿童1 259人，其中男生627人，女生632人，8岁423人，9岁419人，10岁417人。尿碘中位数为164.58 ug/L,盐碘中位数24.02 ug/L,碘盐覆盖率93.01%,合格碘盐食用率91.47%;甲状腺肿大33人，肿大率2.62%;甲状腺容积与性别无关(Z=-0.736,P=4.602),随年龄、身高、体重、体质指数、体表面积增加而增大(Spearman相关系数分别为0.30、0.41、0.44、0.31、0.47,偏相关系数分别为0.08、0.13、0.25、-0.03、0.18);年龄、身高、体表面积、体重的标准偏回归系数分别为0.09、0.10、0.15、0.23,四者比例为1∶1.22∶1.75∶2.71。结论 厦门市儿童甲状腺容积受多种因素影响，评价儿童甲状腺容积大小时除年龄外还应考虑身高、体重、体表面积的影响。更多还原

【Abstract】 Objective To analyze the factors influencing thyroid volume of children aged 8-10 years in Xiamen City, and to provide a scientific basis for scientifically evaluating the prevention and treatment effect of iodine deficiency disorders and adjusting the evaluation index of thyroid volume. Methods We recruited 8-10-year-old non-boarding students from one primary school each selected in each east, west, south, north and middle part of each district in the six districts of Xiamen City. Random urine samples, salt samples at home, thyroid volume, height and body weight were collected once. Results A total of 1,259 children aged 8-10 years in Xiamen City were selected, including 627 boys, 632 girls, 423 children aged 8 years, 419 children aged 9 years and 417 children aged 10 years. The median urinary iodine was 164.58 ug/L, the median salt iodine 24.02 ug/L, the coverage rate of iodized salt 93.01%, and the consumption rate of qualified iodized salt 91.47%. There were 33 children with goiter, with the goiter rate being 2.62%. The thyroid volume was independent of sex(Z=-0.736, P=4.602), but increased with age, height, body weight, body mass index and body surface area(Spearman correlation coefficients were 0.30, 0.41, 0.44, 0.31 and 0.47 respectively, and the partial correlation coefficients were 0.80, 0.13, 0.25,-0.03 and 0.18 respectively). The standard partial regression coefficients of age, height, body surface area and body weight were 0.09, 0.10, 0.15 and 0.23 respectively, and the ratio of them was 1∶1.22∶1.75∶2.71. Conclusions The thyroid volume of children in Xiamen City is influenced by many factors, and the influence of height, weight and body surface area should be considered besides age when evaluating the children’s thyroid volume.更多还原