【摘要】 目的 探讨中老年脑卒中运动性失语(Broca aphasia, BA)患者久坐行为时间与卒中后抑郁(post-stroke depression, PSD)发病风险的相关性。方法 于2021年1月—2022年5月采用方便抽样法选取新疆某三级甲等医院康复科和神经内科收治的中老年脑卒中BA患者112例为研究对象。采用一般资料调查表、脑卒中失语抑郁量表(Stroke Aphasia Depression Questionnaire, SADQ)、久坐行为评估对研究对象进行问卷调查。采用Pearson相关分析法和logistic回归模型对久坐行为时间PSD发病风险关系进行分析。结果 112例脑卒中BA患者每日久坐行为时间(6.57±2.09)h,每日久坐行为时间≥5 h患者66例(58.9%),SADQ评分为(20.72±4.35)分，PSD发生率为44.6%。单因素分析表明，性别、年龄、职业状态、婚姻状况、个人月收入、居住方式、合并慢性病、波士顿失语诊断测验(Boston diagnostic aphasia examination, BDAE)评分、美国国立卫生院脑卒中量表(National Institutes of Health Stroke Scale, NIHSS)评分、久坐行为时间与PSD具有相关性(P均<0.05)。相关性分析结果显示，久坐行为时间与SADQ总分呈正相关(r=0.450,P<0.05)。多因素logistic回归分析结果显示，久坐组[OR=1.527,95%CI(1.168～1.995)]与PSD患病风险相关，控制混杂因素后结果无明显变化。结论 中老年脑卒中BA患者久坐行为时间与PSD发病风险呈正相关，医务人员应重视减少中老年脑卒中BA患者久坐行为时间健康教育，鼓励患者增加社会交往，减少PSD发生发展。更多还原

【Abstract】 Objective To explore the correlation between sedentary behavior time and post-stroke depression(PSD) risk in middle-aged and elderly stroke patients with Broca aphasia(BA). Methods Convenient sampling method was used to select 112 middle-aged and elderly stroke patients with BA hospitalized in rehabilitation department and neurology department of a grade-A tertiary hospital in Xinjiang from January 2021 to May 2022. General information questionnaire, Stroke Aphasia Depression Questionnaire and sedentary behavior assessment were employed to investigate the subjects. Pearson correlation analysis and logistic regression model were applied to analysis of the relationship between sedentary behavior time and the risk of PSD. Results The 112 stroke patients with BA had sedentary behavior time of(6.57±2.09) h/d, and 66(58.9%) patients had sedentary behavior time of ≥ 5 h/d. The SADQ score was(20.72±4.35), and the incidence rate of PSD was 44.6%. Univariate analysis showed that gender, age, occupational status, marital status, monthly personal income, residence style, accompanying with chronic diseases, score of Boston Diagnostic Aphasia Examination(BDAE), score of National Institutes of Health Stroke Scale(NIHSS), and sedentary behavior time were correlated with PSD(all P<0.05). The results of correlation analysis displayed that the sedentary behavior time was positively correlated with the total score of SADQ(r=0.450, P<0.05). The results of multivariate logistic regression analysis revealed that the sedentary group(OR=1.527, 95%CI:1.168-1.995) was associated with the risk of PSD, and no significant change was found in the results after controlling for the confounding factors. Conclusion The sedentary behavior time of the middle-aged and elderly stroke patients with BA is positively correlated with the risk of PSD.Medical staff should pay special attention to health education about reducing the sedentary behavior time of middle-aged and elderly stroke patients with BA, and encourage the patients to increase social interaction so as to reduce the occurrence and development of PSD.更多还原