【摘要】 目的 由于受基础疾病、生活习惯及传统观念等因素影响，老年人群社区获得性金黄色葡萄球菌流行具有一定的特点。本研究通过调查太原市老年人群社区获得性金黄色葡萄球菌的流行病学特征，以期为老年人群开展针对性健康教育及临床治疗经验性用药提供科学依据。方法 2019年4月—2020年7月，抽取太原市4个行政区域的9个成熟社区，对年龄≥60岁的626名老年人进行问卷调查与病原学检测。采用χ~2检验、Kruskal-Wallis H检验和logistic回归模型分析研究社区老年人群金黄色葡萄球菌(SA)与社区获得性耐甲氧西林金黄色葡萄球菌(community-acquired methicillin-resistant Staphylococcus aureus,CA-MRSA)携带情况及相关危险因素。结果 626名社区老年人中有35名携带SA,携带率为5.6%,其中，5人携带CA-MRSA,携带率为0.8%。基础疾病数量(χ~2=9.229,P=0.026)、家庭结构(χ~2=5.746,P=0.017)、是否吃隔夜饭(χ~2=4.990,P=0.025)、近3个月是否使用抗菌药物(χ~2=4.705,P=0.030)组间SA携带率差异有统计学意义。多因素分析显示，社区老年人群SA携带的影响因素有家庭结构(OR=2.523,95%CI:1.235～5.155,P=0.011),吃隔夜饭(OR=2.496,95%CI:1.105～5.634,P=0.028),近3个月是否使用抗菌药物(OR=2.394,95%CI:1.019～5.620,P=0.045)。结论 太原市老年人群SA携带情况已与医疗机构老年患者SA携带水平相当，CA-MRSA携带水平低于全国平均水平，应持续加强社区老年人群健康宣教与抗菌药物管理，关注老年人群健康。更多还原

【Abstract】 Objective Due to the influence of underlying diseases, living habits and traditional ideas, the prevalence of community-acquired Staphylococcus aureus in elderly has certain characteristics. To investigate the epidemiological characteristics of community-acquired Staphylococcus aureus towards the elderly in Taiyuan, so as to provide evidence for health education and clinical the empirical use of antibacterial agents. Methods A total of 626 residents aged 60 years or older were selected from nine communities of four administrative regions in Taiyuan for face to face questionnaire survey and pathogenic detection from April 2019 to July 2020. Chi square test, Kruskal-Wallis H test and logistic regression model were used to analyze the carrying status and related risk factors of Staphylococcus aureus(SA) and community-acquired methicillin-resistant Staphylococcus aureus(CA-MRSA) in the elderly population in the community. Results Among the 626 elderly people in the community, 35 carried SA, with a carrying rate of 5.6%, of which 5 carried CA-MRSA, with a carrying rate of 0.8%. There was statistically significant difference in SA carrier rate in number of underlying diseases(χ~2=9.229, P=0.026), family structure(χ~2=5.746, P=0.017), whether to eat overnight meal(χ~2=4.990, P=0.025), whether to use antibacterial drugs in the past 3 months(χ~2=4.705, P=0.030). Multivariate logistics analysis showed that family structure(OR=2.523, 95% CI: 1.235-5.155, P=0.011), eating leftover(OR=2.496, 95% CI: 1.105-5.634, P=0.028), using of antibiotic in recently three month(OR=2.394, 95% CI: 1.019-5.620, P=0.045) were influencing factors of SA carrying. Conclusion The SA carrying level of the elderly population in Taiyuan is comparable to that of the elderly patients in medical institutions, and the CA-MRSA carrying level is lower than the national average. It is necessary to further strengthen the promotion of health education and antimicrobial management.更多还原