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肿瘤治疗引起口腔黏膜炎的治疗研究进展

Progress in prevention and treatment of chemoradiotherapy associated oral mucositis

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【作者】 闫慧颖洪志超张玉皎唐睿毛芮汤依群

【Author】 YAN Huiying;HONG Zhichao;ZHANG Yujiao;TANG Rui;MAO Rui;TANG Yiqun;China Pharmaceutical University;

【通讯作者】 汤依群;

【机构】 中国药科大学

【摘要】 口腔黏膜炎是癌症患者在接受放化疗时常见的并发症,其严重程度关系到患者生活质量和临床疗效,是肿瘤治疗药学监护的重要课题。本文从口腔黏膜炎发生机制、临床表现及临床治疗方案等角度介绍肿瘤治疗诱发的口腔黏膜炎防治现状;探讨“湿性愈合”理论应用于口腔黏膜炎治疗的可能性,以期将这一技术广泛运用于缓解口腔黏膜炎症状,并联合其他治疗药物,促进溃疡高质量愈合。

【Abstract】 Oral mucositis is a common complication of cancer patients receiving chemoradiotherapy, which is highly related to the patients’ life quality and clinical efficacy.Thus the management of oral mucositis is becoming an important part of pharmaceutical care of cancer patients.In this paper, the current status of prevention and treatment of oral mucositis induced by cancer therapy was introduced from the perspectives of its pathogenesis, clinical manifestations and clinical treatment regimens.At the same time, we described the clinical application of "wet healing" at the present stage, with a view to applying this technology combining with other drugs in order to improve the quality of wound healing.

【关键词】 口腔黏膜炎癌症化疗放疗
【Key words】 oral mucositiscancerchemotherapyradiotherapy
  • 【文献出处】 现代肿瘤医学 ,Journal of Modern Oncology , 编辑部邮箱 ,2023年12期
  • 【分类号】R730.5
  • 【下载频次】296
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