【摘要】 采用响应面法优化超声提取苦瓜皂苷的最佳工艺，并考察最佳提取工艺条件下提取物对α-葡萄糖苷酶的抑制活性。试验结果表明，超声提取苦瓜皂苷的最佳工艺条件为固液比1∶15（g/mL）、乙醇浓度75%、超声时间95 min、提取温度50℃，在该条件下苦瓜皂苷的提取率可达2.21%，其对α-葡萄糖苷酶抑制的IC₅₀值为5.48 mg/mL。更多还原

【Abstract】 Response surface methodology was used to optimize the ultrasonic extraction process of saponins from Momordica charantia,and the inhibitory activity of the extract on α-glucosidase under the optimal extraction process conditions was investigated. The experimental results showed that the optimal extraction conditions for ultrasonic extraction of saponins from Momordica charantia were solid-liquid ratio 1∶15（g/mL）,ethanol concentration 75%,ultrasonic time 95 min,extraction temperature 50 ℃. Under such conditions,the extraction rate of saponins from Momordica charantia was up to 2.21%,and the IC₅₀value against α-glucosidase was 5.48 mg/mL.更多还原