【摘要】 由于心血管疾病会引发血管狭窄和栓塞等问题,人造血管支架的研究成为热点。由于血栓形成及内膜增生等问题尚未得到妥善解决,长期通畅性小口径人造血管的研究仍是难点。阐述了静电纺丝技术制备小口径人造血管的优势,详细介绍了小口径人造血管的性能要求及各常用选材的应用,并分析其优势与不足。介绍了表面改性对血管材料性能以及组织再生方面的影响。最后,展望了静电纺丝制备小口径人造血管的研究方向。更多还原

【Abstract】 Due to the issues of vascular stenosis and embolism caused by cardiovascular diseases, research on artificial vascular stents has become a hot topic. Especially due to issues such as thrombosis and intimal hyperplasia that have not been properly addressed, the research on long-term patency of small caliber artificial blood vessels remains a challenge. The advantages of electrospinning technology in preparing small caliber artificial blood vessels are elaborated, and a detailed introduction to the performance requirements of small caliber artificial blood vessels is made and the applications of various commonly used materials are introduced, and their advantages and disadvantages are analyzed. The impact of surface modification on the properties of vascular materials and tissue regeneration is introduced. Finally, the future research directions for the preparation of small caliber artificial blood vessels by electrospinning are prospected.更多还原