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痹克颗粒致药物性肝损伤1例
A case of drug-induced liver injury caused by Bike Granules
【摘要】 1例47岁男性患者,因“痛风”发作,自行服用痹克颗粒(10 g, po, tid)治疗。服药后约10 d,出现“全身皮肤黄染、巩膜黄染”入院治疗。入院当日肝功能示总胆红素40μmol·L-1,非结合胆红素14.2μmol·L-1,碱性磷酸酶167.1 U·L-1,总胆汁酸70.1μmol·L-1,谷丙转氨酶374.4 U·L-1,谷氨酰转肽酶645.8 U·L-1,谷草转氨酶291.3 U·L-1。考虑痹克颗粒致药品不良反应,停药保肝治疗1月余后,患者肝功恢复正常。
【Abstract】 A 47-year-old male patient was treated with Bike Granules(10 g, po, tid) due to a gout attack.About 10 days after taking the medicine, he was hospitalized with "yellow skin staining all over the body and yellow sclera".Liver function on admission day: TBiL 40 μmol·L-1,UCB 14.2 μmol·L-1,ALP 167.1 U·L-1,TBA 70.1 μmol·L-1,ALT 374.4 U·L-1,γ-GT 645.8 U·L-1,and AST 291.3 U·L-1.Adverse drug reaction considered to be related to Bike Granules.The patient′s liver function returned to normal more than 1 month after discontinuation of the treatment.
【Key words】 Bike Granules; Drug-induced liver injury; Adverse drug reaction;
- 【文献出处】 药学研究 ,Journal of Pharmaceutical Research , 编辑部邮箱 ,2023年01期
- 【分类号】R969.3
- 【下载频次】17