【摘要】 【目的】对针刺法治疗失眠症伴抑郁障碍文献进行Meta分析和系统评价。【方法】通过计算机检索中国知网期刊全文数据库（CNKI）、万方学术期刊全文数据库（Wanfang）、维普中文科技期刊数据库（VIP）、中国生物医学数据库（CBM）、美国生物医学信息检索系统（PubMed）、荷兰医学文摘（Embase）、国际循证医学图书馆（Cochrane Library）等各大数据库针刺治疗失眠症伴抑郁障碍的临床随机对照试验文献，检索时间为各数据库自建库以来至2021年2月。由2名评价者独立检索、提取资料和评估方法学质量后，采用RevMan 5.3软件进行Meta分析。【结果】最终纳入15项研究，共计1 161例失眠症伴抑郁障碍患者，分析结果显示：试验组（针刺治疗）与常规西药对照组比较：（1）匹兹堡睡眠质量指数（PSQI）评分发现，针刺治疗后PSQI评分低于西药治疗，且差异具有统计学意义[MD=-0.52,95%CI(-0.79,-0.25),P<0.000 01];(2)汉密尔顿抑郁量表（HAMD）评分发现，针刺治疗后HAMD评分低于西药治疗，差异具有统计学意义[MD=-2.28,95%CI(-2.51,-2.04,P<0.000 01];(3)抑郁自评量表（SDS）评分发现，针刺治疗后的HAMD评分低于西药治疗，差异具有统计学意义[MD=-0.34,95%CI(-0.57,-0.10),P<0.000 01]。【结论】针刺治疗失眠症伴抑郁障碍在改善睡眠质量、抑郁及焦虑症状方面疗效优于西药治疗，具有较好的临床疗效。更多还原

【Abstract】 Objective To conduct a systematic review and meta-analysis of acupuncture therapy for insomnia complicated with depressive disorder. Methods The literature of clinical randomized controlled trials of acupuncture for insomnia complicated with depressive disorder was searched by computer through major databases such as CNKI,Wanfang,VIP,CBM,PubMed,Embase,Cochrane Library and other major databases,the literature on clinical randomized controlled trials of acupuncture for insomnia complicated with depressive disorders was searched independently by 2 evaluators for each database from the time of its establishment to February 2021.Meta-analysis was performed using RevMan 5.3 software after independent searching, data extraction and assessment of methodological quality by the 2 evaluators. Results Fifteen studies with a total of 1 161 patients with insomnia complicated with depressive disorder were finally included,and the results of the analysis showed that:the trial group compared with the conventional western medicine control group:(1)the Pittsburgh Sleep Quality Index(PSQI)scores were found to be lower after acupuncture treatment than after western medicine treatment,and the difference was statistically significant [MD =-0.52,95% CI(-0.79,-0.25),P<0.000 01];(2)Hamilton Depression Scale(HAMD)scores showed that HAMD scores after acupuncture treatment were lower than those after western medicine treatment,and the difference was statistically significant [MD =-2.28,95% CI(-2.51,-2.04,P<0.000 01];(3)Self-Rating Depression Scale(SDS)scores found that HAMD scores after acupuncture treatment were lower than those after western medicine treatment with the difference being statistically significant[MD=-0.34, 95% CI(-0.57,-0.10), P<0.000 01]. Conclusion Acupuncture treatment for insomnia complicated with depressive disorder is more effective than western medicine treatment in improving sleep quality,depression and anxiety symptoms,with better clinical efficacy.更多还原