【摘要】 目的 探讨肌肉减少症(简称肌少症)与老年H型高血压的相关性研究。方法 选取2021年12月至2022年10月于内蒙古自治区人民医院老年医学中心、老年门诊及体检中心的老年患者(年龄≥60岁)409例，根据高血压的诊断标准分为老年高血压组和老年非高血压组，对两组合并肌少症人数进行统计学分析；根据同型半胱氨酸测定将老年高血压分为H型高血压组和非H型高血压组，对两组合并肌少症人数及一般资料、生化指标进行统计学分析。经回归分析，探讨肌少症是否为老年H型高血压的独立危险因素。结果 (1)老年高血压组合并肌少症人数较非高血压组多，差异有统计学意义(P<0.05)。(2)老年H型高血压组合并肌少症人数较非H型高血压组多，差异有统计学意义(P<0.05)。(3)老年H型高血压肌少症组男性多于女性，差异有统计学意义(P<0.05)。(4)老年H型高血压组Hcy、CysC高于非H型高血压组，差异均有统计学意义(P<0.05)。(5)老年H型高血压肌少症组左右臂及左右腿肌肉量、ASM、ASMI、握力均低于非肌少症组，差异有统计学意义(P<0.05)。(6)Spearman相关分析显示，肌少症、CysC均与H型高血压呈正相关(P<0.05)。logistic回归分析显示，肌少症、CysC是老年H型高血压发生的危险因素(P<0.05)。Spearman相关分析显示，Hcy、男性均与H型高血压合并肌少症呈正相关(P<0.05),logistic回归分析显示，Hcy、男性是H型高血压合并肌少症的危险因素(P<0.05)。结论 肌少症是老年H型高血压的危险因素，Hcy是老年H型高血压合并肌少症的危险因素。更多还原

【Abstract】 Objective To investigate the correlation between sarcopenia and H-type hypertension in the elderly.Methods A total of 409 elderly patients(age≥60 years) in Geriatric medicine Center, geriatric outpatient clinic and physical examination center of Inner Mongolia Autonomous Region People’s Hospital from December 2021 to October 2022 were selected. According to the diagnostic criteria of hypertension, they were divided into geriatric hypertension group and geriatric non-hypertension group. According to homocysteine measurement, elderly hypertension was divided into H-type hypertension group and non-H-type hypertension group. The number of patients with sarcopenia, general data and biochemical indexes of the two groups were statistically analyzed. To explore whether sarcopenia is an independent risk factor for H-type hypertension in the elderly by regression analysis.Results(1)The number of elderly patients with hypertension combined with sarcopenia was higher than that of non-hypertension group, and the difference was statistically significant(P<0.05).(2)The number of elderly patients with H-type hypertension combined with sarcopenia was higher than that of non-H-type hypertension group, and the difference was statistically significant(P<0.05).(3)There were more males than females in the H-type hypertensive sarcopenia group(P<0.05).(4)Hcy and CysC in the elderly H-type hypertension group were higher than those in the non-H-type hypertension group, and the differences were statistically significant(P<0.05).(5)The muscle mass, ASM, ASMI and grip strength of the left and right arms, left and right legs in the H-type hypertensive sarcopenia group were lower than those in the non-sarcopenia group(P<0.05).(6)Spearman correlation analysis showed that sarcopenia and CysC were positively correlated with H-type hypertension(P<0.05). logistic regression analysis showed that sarcopenia and CysC were risk factors for H-type hypertension in the elderly(P<0.05).Spearman correlation analysis showed that Hcy and male were positively correlated with H-type hypertension combined with sarcopenia(P<0.05).logistic regression analysis showed that Hcy and male were risk factors for H-type hypertension combined with sarcopenia(P<0.05).Conclusion Sarcopenia is a risk factor for H-type hypertension in the elderly. Hcy is a risk factor for sarcopenia in elderly patients with H-type hypertension.更多还原