【摘要】 目的 探讨颈动脉支架植入术(CAS)后持续性低血压的影响因素。方法 回顾性分析140例行CAS治疗的颈动脉狭窄患者的临床资料，并依据术后持续性低血压发生情况将患者分为发生组与未发生组。比较两组患者的资料，并应用多因素logistic回归分析CAS术后持续性低血压的影响因素。结果 140例颈动脉狭窄患者中，有40例患者CAS术后发生持续性低血压，发生率为28.57%(40/140)。两组患者的年龄、术侧狭窄部位、术侧狭窄程度、手术时间、溃疡斑块情况、支架后扩张情况、低血压史的差异均有统计学意义(均P<0.05)。多因素logistic回归分析结果显示，年龄≥65岁、术侧球部狭窄、术侧重度狭窄、手术时间≥1 h、有溃疡斑块、有支架后扩张、有低血压史为CAS术后持续性低血压的独立危险因素(均P<0.05)。结论 年龄≥65岁、术侧球部狭窄、术侧重度狭窄、手术时间≥1 h、有溃疡斑块、有支架后扩张、有低血压史为颈动脉狭窄患者CAS术后持续性低血压的独立危险因素。更多还原

【Abstract】 Objective To investigate the influencing factors for persistent hypotension after carotid artery stenting(CAS). Method The clinical data of 140 patients with carotid artery stenosis treated with CAS were retrospectively analyzed, and the patients were divided into the occurrence group or the non-occurrence group according to the occurrence of postoperative persistent hypotension. The data of the two groups were compared, and multivariate logistic regression was used to analyze the influencing factors for persistent hypotension after CAS. Results Among the 140 patients with carotid artery stenosis, 40 patients developed persistent hypotension after CAS, with an incidence of 28.57%(40/140). There were statistically significant differences in age, stenosis site on the surgical side, stenosis severity on the surgical side, surgery time, ulcer plaque condition, stent post-dilatation condition, and history of hypotension between the two groups(all P<0.05). The results of multivariate logistic regression analysis showed that age ≥65 years, bulb stenosis on the surgical side, severe stenosis on the surgical side, surgery time ≥ 1 h, ulcer plaque, stent post-dilation, and a history of hypotension were independent risk factors for persistent hypotension after CAS(all P<0.05). Conclusion Age≥ 65 years, bulb stenosis on the surgical side, severe stenosis on the surgical side, surgery time ≥ 1 h, ulcer plaque, stent post-dilation, and a history of hypotension are independent risk factors for persistent hypotension after CAS in patients with carotid artery stenosis.更多还原