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低流行状态下老年麻风患者的临床和流行病学特征研究
Clinical and epidemiological characteristics of elderly leprosy patients in low prevalence of leprosy
【摘要】 目的:了解陕西省老年麻风患者临床和流行病特征。方法:通过中国麻风管理信息系统(LEPMIS),对陕西省2004年1月至2022年1月收治的麻风患者进行回顾性描述性研究。结果:2004年1月至2022年1月期间,该地区共收治新发麻风病例323例,其中54例(16.7%)≥60岁,平均年龄为67.0岁,77.8%为男性;96.3%为低收入人群,57.4%文化程度低下(文盲或半文盲),79.6%有婚史,29.6%为家内传染。70.4%查菌结果为阳性,其中多菌型比例高达83.3%。虽然确诊时存在严重皮损(皮损>5块)的患者比例高达75.9%,存在严重神经损害(神经≥2条损害)的比例高达68.5%,二级畸残的比例高达53.7%,但83.3%的患者确诊时无明显的麻风反应。结论:本地区老年麻风患者伴随严重的皮肤、神经损害及畸残风险,提示在此人群中可能存在较长的诊断延迟期。
【Abstract】 Objective: To investigate the epidemic and clinical features of leprosy cases among the elderly population reported in Shaanxi Province. Methods: Descriptive analysis of data of leprosy patients in Shaanxi Province from January 2004 to January 2022 through LEPMIS were performed. Results: 323 new leprosy cases were found, of which 54 cases(16.7%) were elderly patients(over 60 years old), with an average age of 67.0 years old. Among these elderly patients, 77.8% were males, 96.3% of the elderly patients were low-income population, 57.4% had low education level(illiterate or semi-illiterate), 79.6% had marriage history, and 29.6% were infected at home, 70.4% were positive for bacteria, with the proportion of multi-bacteria type as high as 83.3%. Although the proportion of serious skin lesions(skin lesions > 5) was as high as 75.9%, the proportion of serious nerve lesions(nerves ≥2 lesions) was as high as 68.5%, and the proportion of secondary deformity was as high as 53.7%, there were still 83.3% had no leper reaction. Conclusion: The elderly patients with leprosy have more serious skin and nerve damage, and at the same time, and the high risk of disability, which suggests that there may be a long delay in diagnosis in this population.
- 【文献出处】 中国麻风皮肤病杂志 ,China Journal of Leprosy and Skin Diseases , 编辑部邮箱 ,2023年02期
- 【分类号】R755;R181.3
- 【下载频次】8