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低流行状态下老年麻风患者的临床和流行病学特征研究

Clinical and epidemiological characteristics of elderly leprosy patients in low prevalence of leprosy

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【作者】 李鸽张宇晨宋运龙张虹王耀斐王冠

【Author】 LI Ge;ZHANG Yuchen;SONG Yunlong;ZHANG Hong;WANG Yaofei;WANG Guan;Shaanxi Provincial Institute for Endemic Disease Control;Shaanxi Provincial Institute for Skin Disease and STD Control;School of Public Health,Xi’an Jiaotong University Health Science Center;Shaanxi Provincial Centre for Disease Control and Prevention;

【通讯作者】 宋运龙;张虹;

【机构】 陕西省地方病防治研究所陕西省皮肤性病防治所西安交通大学医学部公共卫生学院陕西省疾病预防控制中心

【摘要】 目的:了解陕西省老年麻风患者临床和流行病特征。方法:通过中国麻风管理信息系统(LEPMIS),对陕西省2004年1月至2022年1月收治的麻风患者进行回顾性描述性研究。结果:2004年1月至2022年1月期间,该地区共收治新发麻风病例323例,其中54例(16.7%)≥60岁,平均年龄为67.0岁,77.8%为男性;96.3%为低收入人群,57.4%文化程度低下(文盲或半文盲),79.6%有婚史,29.6%为家内传染。70.4%查菌结果为阳性,其中多菌型比例高达83.3%。虽然确诊时存在严重皮损(皮损>5块)的患者比例高达75.9%,存在严重神经损害(神经≥2条损害)的比例高达68.5%,二级畸残的比例高达53.7%,但83.3%的患者确诊时无明显的麻风反应。结论:本地区老年麻风患者伴随严重的皮肤、神经损害及畸残风险,提示在此人群中可能存在较长的诊断延迟期。

【Abstract】 Objective: To investigate the epidemic and clinical features of leprosy cases among the elderly population reported in Shaanxi Province. Methods: Descriptive analysis of data of leprosy patients in Shaanxi Province from January 2004 to January 2022 through LEPMIS were performed. Results: 323 new leprosy cases were found, of which 54 cases(16.7%) were elderly patients(over 60 years old), with an average age of 67.0 years old. Among these elderly patients, 77.8% were males, 96.3% of the elderly patients were low-income population, 57.4% had low education level(illiterate or semi-illiterate), 79.6% had marriage history, and 29.6% were infected at home, 70.4% were positive for bacteria, with the proportion of multi-bacteria type as high as 83.3%. Although the proportion of serious skin lesions(skin lesions > 5) was as high as 75.9%, the proportion of serious nerve lesions(nerves ≥2 lesions) was as high as 68.5%, and the proportion of secondary deformity was as high as 53.7%, there were still 83.3% had no leper reaction. Conclusion: The elderly patients with leprosy have more serious skin and nerve damage, and at the same time, and the high risk of disability, which suggests that there may be a long delay in diagnosis in this population.

【关键词】 麻风老年流行病学
【Key words】 leprosyagedepidemiology
【基金】 陕西省卫生健康科研基金项目(编号:2022E007)
  • 【文献出处】 中国麻风皮肤病杂志 ,China Journal of Leprosy and Skin Diseases , 编辑部邮箱 ,2023年02期
  • 【分类号】R755;R181.3
  • 【下载频次】8
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