【摘要】 微小残留病(MRD)已被常规用于急性髓细胞白血病(AML)患者的疗效评估和复发预测。本文从异基因造血干细胞移植适应证、移植方式、预处理方案以及移植后复发预防等方面讨论了MRD指导的个体化分层治疗。未来的研究应聚焦AML患者MRD检测及干预新方法的建立。更多还原

【Abstract】 Minimal residual disease(MRD) has been used routinely for curative effect evaluation and relapse prediction for patients with acute myeloid leukemia(AML). It discussed MRD directed individual therapy for AML in view of transplant indications, transplant modality selection, conditioning regimen and relapse prevention after allogeneic stem cell transplantation. Future directions should focus on the establishment of new methods for MRD detection and novel strategies for MRD intervention.更多还原