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CT术前预测甲状腺乳头状癌颈部淋巴结转移的价值及危险因素分析

Value of Preoperative CT in Predicting Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma and Its Risk Factors

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【作者】 张联合曾炳亮李虹璐李滋聪

【Author】 ZHANG Lian-he;ZENG Bing-liang;LI Hong-lu;LI Zi-cong;Department of Radiology,Nanfeng People’s Hospital;Department of Imaging,Jiangxi Provincial People’s Hospital;

【通讯作者】 曾炳亮;

【机构】 南丰县人民医院放射科江西省人民医院影像科

【摘要】 目的 分析术前CT对甲状腺乳头状癌(PTC)患者颈部淋巴结转移的预测价值。方法 选取2017年5月至2021年9月收治的100例PTC患者,均经手术病理确诊。根据术后转移情况将其分为转移组(n=30)和未转移组(n=70)。术前均行平扫期、动脉期和静脉期增强CT扫描,计算原发病灶CT值、净增CT值与标准化CT值,并对患者颈部淋巴结转移危险因素进行分析。结果 转移组患者CT值、净增CT值和标准化CT值均高于未转移组(P<0.05);单因素分析结果显示,转移组患者年龄≥50岁、多发灶、被膜侵犯、外侵犯所占比均明显高于未转移组(P<0.05);多因素分析结果显示:年龄≥50岁、被膜侵犯、外侵犯为PTC颈部淋巴结转移的危险因素(P<0.05)。结论 PTC患者原发病灶静脉期CT值对颈部淋巴结转移有预测作用;年龄≥50岁、被膜侵犯、外侵犯与PTC颈部淋巴结转移密切相关。

【Abstract】 Objective To analyze the value of preoperative CT in predicting cervical lymph node metastasis in patients with papillary thyroid carcinoma(PTC).Methods One hundred PTC patients admitted from May 2017 to September 2021 and confirmed by surgical pathology were selected in this study.According to postoperative metastasis, these patients were divided into metastasis group(n=30) and non-metastasis group(n=70).All patients underwent plain, arterial and venous phase contrast-enhanced CT scans before surgery, and primary lesion CT value, net incremental CT value and normalized CT value were calculated.In addition, the risk factors for cervical lymph node metastasis were analyzed.Results The CT value, net incremental CT value and standardized CT value in the metastasis group were higher than those in the non-metastasis group(P<0.05).Univariate analysis showed that the proportions of patients aged ≥50 years and patients with multiple foci, capsule invasion or external invasion in the metastasis group were higher than those in the non-metastasis group(P<0.05).Multivariate analysis showed that age ≥50 years old, capsular invasion and external invasion were risk factors for cervical lymph node metastasis in PTC(P<0.05).Conclusion The venous phase CT value of primary tumor can predict cervical lymph node metastasis in PTC patients.Age ≥ 50 years old, capsule invasion and external invasion are closely related to cervical lymph node metastasis in PTC.

【基金】 江西省卫健委科技计划(202130073)
  • 【文献出处】 实用临床医学 ,Practical Clinical Medicine , 编辑部邮箱 ,2023年01期
  • 【分类号】R736.1
  • 【下载频次】8
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