【摘要】 目的 探讨疾病获益感指导下的心理干预对食管癌放疗患者心理痛苦、癌因性疲乏、应对方式等的影响。方法 将82例食管癌患者按随机数字表法分为观察组和对照组，每组41例。对照组给予常规护理干预，观察组在对照组基础上给予疾病获益感指导下的心理干预，干预4周。比较两组干预前后心理痛苦、应对方式、癌因性疲乏、营养状况(前白蛋白、白蛋白、转铁蛋白)、生存质量等指标。结果 干预后两组心理痛苦温度计、生活质量核心量表评分均较干预前降低，且观察组低于对照组(P<0.01)。干预后两组简易应对方式问卷的积极应对和消极应对维度评分均较干预前改善，观察组优于对照组，差异有统计学意义(P<0.01)。干预后两组Piper疲乏自评量表总分及躯体疲乏、认知疲乏、情感疲乏、综合疲乏评分均较干预前降低，且观察组低于对照组，差异有统计学意义(P<0.01)。干预后两组前白蛋白、白蛋白、转铁蛋白水平均较干预前升高，且观察组高于对照组，差异有统计学意义(P<0.01)。结论 疾病获益感指导下的心理干预可有效调节食管癌放疗者的应对方式，缓解其心理痛苦、癌因性疲乏，并改善营养状态及生存质量。更多还原

【Abstract】 Objective To explore the influences of benefit finding guided psychological intervention on distress, cancer related fatigue and coping styles in esophageal cancer patients undergoing radiotherapy. Methods Eighty-two esophageal cancer patients were divided into observation and control group according to random number table method, with 41 cases in each group. Control group received routine nursing intervention and observation was plus benefit finding guided psychological intervention on the basis of control group for 4 weeks. Such indexes were compared between two groups as pre-and post-intervention distress, coping style, cancer-related fatigue, nutritional status [prealbumin(PA), albumin(SA), transferrin(TF)], and quality of life. Results After intervention scores on the Distress Thermometer and Quality of Life Questionnaire Core 30 in both groups lowered compared with pre-intervention and those were lower in observation than control group(P<0.01). After intervention scores on positive and negative coping of the Simplified Coping Style Questionnaire in both groups improved compared with pre-intervention and those did more significantly in observation than control group(P<0.01). After intervention the total, somatic, cognitive, emotional, and comprehensive fatigue scores of Piper Fatigue Scale in both groups lowered compared with pre-intervention and those were lower in observation than control group(P<0.01). After intervention PA, SA and TF levels elevated in both groups compared with pre-intervention and those were higher in observation than control group(P <0.01).Conclusion Benefit finding guided psychological intervention could effectively regulate coping styles in esophageal cancer patients undergoing radiotherapy,alleviate distress and cancer related fatigue,and improve nutritional status and quality of life.更多还原