【摘要】 目的:了解强迫症患者社会功能及其影响因素。方法:纳入2020年5月至2022年1月在南京脑科医院强迫症专病门诊及住院就诊的278名强迫症患者为研究对象，应用强迫症症状分类量表(OCI-R)、耶鲁布朗强迫量表(Y-BOCS)、贝克抑郁量表(BDI-Ⅱ)、贝克焦虑量表(BAI)评价患者临床症状；席汉残疾量表(SDS)评价患者社会功能受损情况。结果:强迫症患者Y-BOCS得分(21.76±7.08),社会功能总体受损得分(15.59±7.79),工作学习维度得分(5.65±2.88),家庭责任维度得分(4.84±3.00),社交生活维度得分(5.10±2.88)。强迫的洗涤维度、强迫思维、精神中和，焦虑症状，抑郁症状与社会功能总体及分维度受损均存在显著正相关(P<0.05),年龄仅与家庭责任维度相关，检查维度仅与社交生活维度相关。强迫思维症状，强迫、焦虑及抑郁症状严重程度进入强迫症患者社会功能总体受损的回归方程(P<0.05)。抑郁、焦虑症状的中介效应显著。结论:不同症状特点强迫症患者社会功能受损程度及维度存在差异，强迫思维症状，强迫、焦虑及抑郁症状严重程度是社会功能总体受损的影响因素，抑郁、焦虑症状是强迫症患者社会功能受损的中介因素。更多还原

【Abstract】 Objective:To understand the social function of people with obsessive-compulsive disorder and its influencing factors. Method:278 inpatients and outpatients patients with obsessive-compulsive disorder who were treated in the obsessive-compulsive disorder clinic of Nanjing Brain Hospital from May 2020 to January 2022 were receuited.Yale-Brown obsessive compulsive scale, obsessive-compulsive inventory-revised, Beck depression inventory-II and Beck anxiety inventory scales were used to evaluate their clinical symptoms.The Sheehan disability scale(SDS) assesses patients with impaired social functioning. Results:Patients with obsessive-compulsive disorder scored Y-BOCS(21.76±7.08),overall impaired social function(15.59±7.79),work-study dimension(5.65±2.88),family responsibility(4.84±3.00),and social life(5.10±2.88).There were significant positive correlations between compulsive washing dimensions, obsessive thinking, mental neutralization, anxiety symptoms, and depressive symptoms and impairment of social function in all and sub-dimensions(P<0.05),age was only associated with the dimension of family responsibility, and the dimension of examination was only related to the dimension of social life.Obsessive-compulsive thinking symptoms, obsessive-compulsive, anxious, and depressive symptoms severity enter the regression equation for overall impairment of social function in patients with obsessive-compulsive disorder(P<0.05).The mediating effect of depression and anxiety symptoms was significant. Conclusion:Different symptoms and characteristics of patients with obsessive-compulsive disorder have different degrees and dimensions of impaired social function, the dimension of obsessive-compulsive thinking, the severity of obsessive-compulsive and depressive symptoms are the influencing factors of the overall impairment of social function, and Symptoms of depression and anxiety are mediating factors in impaired social function in patients with obsessive-compulsive disorder.更多还原