【摘要】 目的:分析妊娠期高血压疾病(PIH)患者产后抑郁的危险因素。方法:回顾性分析150例PIH患者临床资料，产后6周用爱丁堡产后抑郁量表(EPDS)评估患者抑郁状况，将发生产后抑郁的患者纳入抑郁组14例，其余为非抑郁组136例。采用多因素Logistic回归分析方法分析PIH患者产后抑郁的危险因素。结果:在150例患者中，产后抑郁的发生率为9.33%。妊娠期和产后6周维生素A缺乏(VAD)、高血压疾病家族史、孕产期肠道菌群失调、二十碳五烯酸(EPA)、二十二碳六烯酸(DHA)是患者产后抑郁的独立危险因素(P<0.05)。结论:妊娠期和产后6周VAD、高血压疾病家族史、孕产期肠道菌群失调、EPA、DHA是PIH患者产后抑郁发生的危险因素，可作为防治PIH产后抑郁的新参考。更多还原

【Abstract】 Objective: To analyze the risk factors of postpartum depression in patients with pregnancy induced hypertension(PIH). Method:The clinical data of 150 cases of patients with PIH were retrospectively analyzed.The Edinburgh postnatal depression scale(EPDS) was used to assess the patients’ depression status at 6 weeks postpartum.Patients with postpartum depression were included in the depression group(n=14),and the rest were included in the non-depression group(n=136).Multivariate Logistic regression analysis was used for analyzing the risk factors of postpartum depression in PIH patients. Results:Among 150 patients, the incidence of postpartum depression was 9.33%. Vitamin A deficiency(VAD)during pregnancy and 6 weeks postpartum, family history of hypertension, intestinal flora disorder during pregnancy and perinatal period, eicosapentaenoic acid(EPA),and docosahexenoic acid(DHA) were independent risk factors for postpartum depression(P<0.05). Conclusion: VAD during pregnancy and 6 weeks postpartum, family history of hypertension, intestinal flora disorder during pregnancy and perinatal period, EPA,and DHA are risk factors for postpartum depression in PIH patients, which could be used as a new reference for prevention and treatment of postpartum depression in PIH patients.更多还原