【摘要】 2010年日本胃肠病学会（JSGE）首次发布以循证医学为基础的胆石症临床实践指南，并于2016年进行更新。2023年4月，基于1983年—2019年8月Medline、Cochrane以及Igaku Chuo Zasshi等数据库中关于胆石症相关临床问题及近5年最新文献证据，JSGE发布胆石症循证临床实践指南（2021）。本次修订分别从流行病学、发病机制、诊断、治疗、预后及并发症等方面，对上一版中的临床问题进行回顾并重新划分为三类共52个问题：29个背景问题涉及基础背景知识、19个临床问题和4个需进一步积累证据的未来研究问题，为胆石症患者的临床管理决策提供指导。更多还原

【Abstract】 The Japanese Society of Gastroenterology(JSGE) first published evidence-based clinical practice guidelines for cholelithiasis in 2010, followed by a revision in 2016. In April 2023, JSGE published the 2021 edition of evidence-based clinical practice guidelines for cholelithiasis based on the clinical issues associated with cholelithiasis in the databases such as Medline, Cochrane, and Igaku Chuo Zasshi and the latest evidence in literature published in the past five years. The revised edition reviews related clinical questions in the previous edition from the aspects of the epidemiology, pathogenesis, diagnosis, treatment, prognosis, and complications of cholelithiasis and reclassifies them into three categories, with 52 questions in total, among which there are 29 background questions dealing with basic background knowledge, 19 clinical questions, and 4 future research questions requiring further accumulation of evidence, thereby providing guidance for decision making in the clinical management of patients with cholelithiasis.更多还原