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非酒精性脂肪性肝病的诊断与评估
Diagnosis and evaluation of nonalcoholic fatty liver disease
【摘要】 非酒精性脂肪性肝病(NAFLD)是临床最常见肝病之一,其发病率在全球范围内持续增加。NAFLD包括非酒精性肝脂肪变,并可以进一步进展为非酒精性脂肪性肝炎、肝硬化和肝细胞癌。迄今为止,肝活检被认为是评估肝脂肪变性和纤维化的“金标准”。但鉴于活检在大范围筛查中存在着局限性,用于评估NAFLD各个阶段的非侵入性测试对患者诊断及预后管理的作用显得愈发重要。本文总结了NAFLD诊断与评估的最新进展。
【Abstract】 Nonalcoholic fatty liver disease(NAFLD) is one of the most common causes of liver disease, and its incidence rate continues to increase globally. NAFLD includes nonalcoholic steatosis and can further progress to nonalcoholic steatohepatitis, liver cirrhosis, and hepatocellular carcinoma. So far, liver biopsy has been regarded as the “gold standard” for evaluating hepatic steatosis and fibrosis; however, due to the limitations of biopsy in large-scale screening, noninvasive tests used to evaluate various stages of NAFLD have become increasingly important in the diagnosis and prognosis management of patients. This article summarizes the latest advances in diagnosis and evaluation of NAFLD.
- 【文献出处】 临床肝胆病杂志 ,Journal of Clinical Hepatology , 编辑部邮箱 ,2023年08期
- 【分类号】R575.5
- 【下载频次】62