【摘要】 目的 本研究旨在探讨牙槽骨不同牙位和牙根的不同层面松质骨力学性能，为建立精准的牙槽骨本构模型提供依据。方法 收集新鲜尸体上下颌骨。按照不同牙位(前、后牙区)及牙根不同层面(根颈、根中和根尖部)进行切分，制成独立的牙槽松质骨立方体样本，再进行micro-CT影像学骨密度分析，然后在0.1 mm/min加载速率下进行单轴压缩实验，通过拟合应力-应变曲线，计算出弹性模量，并比较牙槽骨不同部位松质骨弹性模量是否存在差异。结果 在0.1 mm/min单轴压缩下，牙槽松质骨压缩应力-应变曲线呈非线性，上颌各部分牙槽松质骨的弹性模量为340～805 MPa,下颌各部分的牙槽松质骨的弹性模量为107～730 MPa。不同部位的牙槽松质骨弹性模量具有统计学差异，牙槽骨松质骨弹性模量前牙区>后牙区(P<0.05);上下颌牙槽松质骨弹性模量根颈部>根中部，且根中部>根尖部(P<0.01)。结论 上下颌牙槽松质骨弹性模量前牙区>后牙区；根颈部>根中部，且根中部>根尖部。人牙槽松质骨的力学性能受松质骨密度、牙根所在部位、牙根层面等影响。更多还原

【Abstract】 Objective This study aims to explore the mechanical properties of cancellous bone at different tooth positions and at different levels of tooth roots, and to provide a basis for the establishment of an accurate constitutive alveolar bone model. Methods Human maxillary and mandibular bone collected from fresh corpses was divided into several independent cancellous bone cubes at different tooth positions(anterior and posterior regions)and different levels of the roots(cervical, middle and apical regions). After micro-CT imaging bone density analysis, uniaxial compression test was performed at a loading rate of 0.1 mm/min, and the stress-strain curve was linearly fitted. The elastic modulus was calculated and compared to see if there were differences in the elastic modulus of cancellous bone in different parts of the alveolar bone. Results Under uniaxial compression at 0.1 mm/min, the compressive stress-strain curve for human alveolar cancellous bone was non-linear, with moduli of elasticity ranging from 340 to 805 MPa for all parts of the human maxilla and 107 to 730 MPa for all parts of the mandible. The elastic modulus of cancellous bone in different parts of the alveolar bone was statistically different. The elastic modulus of maxillary and mandibular alveolar cancellous bone was greater in the anterior region than in the the posterior region(P<0.05), in the cervical region than in the middle of the root, and in the middle of the root than in the apical region(P<0.01). Conclusion The cancellous bone elastic modulus is greater in the anterior region than in the posterior, in the cervical region than in the middle, and in the middle region than in the apical. The mechanical properties of cancellous bone in human alveolar bone are influenced by the density of cancellous bone, the location of the root, and the root level.更多还原