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基于ICP-MS技术分析不同产地鳖血无机元素差异

Differences Analysis of Inorganic Elements in Sanguis Trionycis from Different Producing Areas Based on ICP-MS Technique

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【作者】 梁艺瑶; 苏雪蓉; 娄悦; 谢颖; 崔小兵; 李锦; 赵晓莉;

【Author】 LIANG Yiyao;SU Xuerong;LOU Yue;XIE Ying;CUI Xiaobing;LI Jin;ZHAO Xiaoli;School of Pharmacy, Nanjing University of Traditional Chinese Medicine;Department of Pharmacy, Jiangsu Province Hospital of Chinese Medicine;

【通讯作者】 李锦;赵晓莉;

【机构】 南京中医药大学药学院; 江苏省中医院药学部;

【摘要】 目的 研究不同产地鳖血的无机元素差异,为其质量评价、安全性评价及综合利用提供依据。方法 建立ICP-MS法测定鳖血中18种无机元素含量并进行方法学考察,采用化学计量学,以聚类分析和主成分分析对不同产地鳖血的无机元素特征进行研究。结果 不同产地鳖血无机元素特征图谱组成基本一致,含量存在一定差异。基于无机元素含量的聚类分析和主成分分析显示,不同区域来源的鳖血能明显区分,Co、V、Fe、K、Sr、Mn、Sn、Na是鳖血的特征元素,浙江省淳安县和湖南省汉寿县的鳖血综合评价较优。结论 建立的方法可用于鳖血无机元素的含量测定,基于无机元素含量结合聚类分析和主成分分析模型,可用于不同产地鳖血的质量评价。

【Abstract】 Objective To explore the characteristics of inorganic elements in Sanguis Trionycis from different producing areas, to provide evidence for its quality evaluation, safety evaluation and comprehensive utilization.Methods An ICP-MS method was established to determine the content of 18 kinds of inorganic elements in Sanguis Trionycis. The characteristics of inorganic elements in Sanguis Trionycis from different producing areas were studied by chemometric analysis, including cluster analysis and principal component analysis. Results The compositions of the characteristic map of Sanguis Trionycis from different producing areas were basically consistent, and the contents were different. Cluster analysis and principal component analysis based on inorganic element content showed that Sanguis Trionycis from different regions could be distinguished obviously, Co, V,Fe, K, Sr, Mn, Sn and Na were characteristic elements of Sanguis Trionycis, and the comprehensive evaluation of Sanguis Trionycis in Chunan County, Zhejiang Province, and Hanshou County, Hunan Province were better.Conclusion The method established in this study can be used to determine the content of multiple inorganic elements in Sanguis Trionycis. The model based on the contents of inorganic elements combined with cluster analysis and principal component analysis can be used to evaluate the quality of Sanguis Trionycis from different producing areas.

【基金】 国家重点研发计划项目(2018YFC1707000);2021年度康缘中药学院创新创业项目(KYXYSC15);2022年江苏省研究生培养创新工程研究生实践创新计划(SJCX22-0794)
  • 【文献出处】 现代中药研究与实践 ,Research and Practice on Chinese Medicines , 编辑部邮箱 ,2023年05期
  • 【分类号】R284
  • 【下载频次】40
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